Airway Mucus Hypersecretion in Bronchiectasis
Conditions
Interventions
test group:Qingfei Litan Decoction
Control group:Carboxymestane Oral Liquid
Sponsors
Xiyuan Hospital, China Academy of Chinese Medical Sciences
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: (1)Outpatients who met the diagnostic criteria for stable bronchiectasis;(2)o smoking within 1 year prior to enrollment, sputum >30 ml per day, and no acute exacerbations due to medical history and physical examination; (3) Aged 18-75 years; (4)TCM syndrome differentiation is phlegm and heat accumulation,Spleen and kidney deficiency; (5) Patients who have at least 3 acute exacerbations in the past year; (6) Those who are willing to follow the doctor's diagnosis and treatment arrangements and sign informed consent.
Exclusion criteria
Exclusion criteria: (1)Patients with dry bronchitis as the main manifestation of hemoptysis; (2) Those who have changed their condition within 4 weeks before enrollment;(3)Patients with severe hematopoietic system diseases, advanced malignant tumors, severe liver and kidney dysfunction;(4)Other circumstances that the investigator considers unfit for inclusion.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| CASA-Q score;24-hour sputum volume; | — |
Secondary
| Measure | Time frame |
|---|---|
| Mucin 5AC;Pulmonary function;Neutrophil elastase;erythrocyte sedimentation rate;Quantitative symptom score;tumor marke;Chest CT scan;C-reactive protein;The number of acute exacerbations of bronchiectasis; | — |
Countries
China
Contacts
Public ContactWang Bing
Xiyuan Hospital, China Academy of Chinese Medical Sciences
Outcome results
None listed