Male infertility
Conditions
Interventions
Chinese herbal medicine treatment group:Chinese herbal medicine treatment
Placebo control group:Placebo treatment
Sponsors
NHC Key Laboratory of Male Reproduction and Genetics, Guangdong Provincial Reproductive Science Institute (Guangdong Provincial Fertility Hospital), Human Sperm Bank of Guangdong Province
Eligibility
Sex/Gender
Male
Age
20 Years to 40 Years
Inclusion criteria
Inclusion criteria: ? Patients aged 20-40 years; ? Azoospermia was determined according to the fifth edition of who manual for laboratory testing of human semen; ? The clinical diagnosis meets the diagnostic criteria of NOA; ? Testicular biopsy report was consistent with the diagnosis of NOA of spermatogenic arrest; ? No cytotoxic drugs or radioactive substances were used in recent 3 months, and the chromosome and AZF gene were normal; ? The development of the second sexual sign is normal, and there is no malformation in the external reproduction; ? Be able to follow up and cooperate with inspection; ? Conform to various dialectical constitutions.
Exclusion criteria
Exclusion criteria: ? Excluding infectious diseases, mental diseases, genetic diseases, endocrine diseases and other systemic diseases; ? Exclude the history of mumps, cryptorchidism and indirect hernia; ? Those who do not meet the inclusion criteria; ? Congenital absence of vas deferens; ? Non compliance with medical advice and poor compliance; ? Those who can't check, follow-up and cooperate with the inspection, and withdraw themselves in the middle; ? Those who are allergic to the drugs used in this study and are not suitable for treatment.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Sperm parameters;Reproductive hormone;Testicular pathology; | — |
Countries
China
Contacts
Public ContactHuang Liu
NHC Key Laboratory of Male Reproduction and Genetics, Guangdong Provincial Reproductive Science Institute (Guangdong Provincial Fertility Hospital), Human Sperm Bank of Guangdong Province
Outcome results
None listed