Acute ischemic stroke
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: (1) Meet the diagnostic criteria of Chinese and Western medicine for acute ischemic stroke; (2) First unilateral onset, within 2 weeks of acute ischemic stroke; (3) Age 18 ~ 75 years old; (4) Stable condition, clear consciousness, Glasgow Coma Scale (GCS) = 13 points; (5) Severity of neurological deficit: National Institutes of Health Stroke Scale (NIHSS) = 4 points (6) No serious disability before admission: Mrs score scale (modified Rankin scale, MRS) = 3 points; (7) No severe aphasia or aphasia, but it does not affect communication and completion of mandatory actions (the severity of aphasia is above grade 2); (8) No hormone and gastrointestinal motility drugs were used within 1 week before the first blood collection; (9) Agree and sign the informed consent form.
Exclusion criteria
Exclusion criteria: (1) Patients with transient ischemic attack (TIA), intracerebral hemorrhage and subarachnoid hemorrhage; (2) Those with viscera in stroke; (3) Patients with other serious diseases such as digestive tract, cardiovascular system, tumor and hematopoietic system that have not been controlled after treatment; (4) Patients with stress ulcer bleeding or severe gastrointestinal bleeding after the onset of the disease; (5) Patients with aphasia, severe cognitive impairment and mental diseases who cannot cooperate with information collection; (6) Those with serious complications, such as cardiopulmonary insufficiency, liver and kidney insufficiency, cancer, dementia, etc., or combined with diseases or disabilities, such as rheumatoid arthritis, gout, amputation and other clinical events that affect the efficacy evaluation of the disease; (7) Fear of acupuncture, or patients with skin diseases caused by acupuncture; (8) Those who are currently participating in other clinical studies and may interfere with the results of this trial.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| NIHSS; | — |
Secondary
| Measure | Time frame |
|---|---|
| MRS;TXNIP;TCM syndrome score of apoplexy;FIM;Hemodynamic index;cleaved caspase-1;a-HIBA;IL-18;FMA;Intestinal flora index;TMAO;IL-1ß;TNF-a;ADL;ASC;NLRP3; | — |
Countries
China