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Clinical Efficacy and Mechanism of Time-Acupoints-Space Acupuncture Najia Method in Early Intervention of Patients with Acute Ischemic Stroke

Clinical Efficacy and Mechanism of Time-Acupoints-Space Acupuncture Najia Method in Early Intervention of Patients with Acute Ischemic Stroke

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ITMCTR
Registry ID
ITMCTR2200006042
Enrollment
Unknown
Registered
2022-05-28
Start date
2022-05-15
Completion date
Unknown
Last updated
2023-02-20

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Acute ischemic stroke

Interventions

control group 2:Routine treatment of Western Medicine
control group 1:Najia method
experimental group:Time-Acupoints-Space Acupuncture Najia method

Sponsors

Second Affiliated Hospital of Yunnan University of Chinese Medicine
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 75 Years

Inclusion criteria

Inclusion criteria: (1) Meet the diagnostic criteria of Chinese and Western medicine for acute ischemic stroke; (2) First unilateral onset, within 2 weeks of acute ischemic stroke; (3) Age 18 ~ 75 years old; (4) Stable condition, clear consciousness, Glasgow Coma Scale (GCS) = 13 points; (5) Severity of neurological deficit: National Institutes of Health Stroke Scale (NIHSS) = 4 points (6) No serious disability before admission: Mrs score scale (modified Rankin scale, MRS) = 3 points; (7) No severe aphasia or aphasia, but it does not affect communication and completion of mandatory actions (the severity of aphasia is above grade 2); (8) No hormone and gastrointestinal motility drugs were used within 1 week before the first blood collection; (9) Agree and sign the informed consent form.

Exclusion criteria

Exclusion criteria: (1) Patients with transient ischemic attack (TIA), intracerebral hemorrhage and subarachnoid hemorrhage; (2) Those with viscera in stroke; (3) Patients with other serious diseases such as digestive tract, cardiovascular system, tumor and hematopoietic system that have not been controlled after treatment; (4) Patients with stress ulcer bleeding or severe gastrointestinal bleeding after the onset of the disease; (5) Patients with aphasia, severe cognitive impairment and mental diseases who cannot cooperate with information collection; (6) Those with serious complications, such as cardiopulmonary insufficiency, liver and kidney insufficiency, cancer, dementia, etc., or combined with diseases or disabilities, such as rheumatoid arthritis, gout, amputation and other clinical events that affect the efficacy evaluation of the disease; (7) Fear of acupuncture, or patients with skin diseases caused by acupuncture; (8) Those who are currently participating in other clinical studies and may interfere with the results of this trial.

Design outcomes

Primary

MeasureTime frame
NIHSS;

Secondary

MeasureTime frame
MRS;TXNIP;TCM syndrome score of apoplexy;FIM;Hemodynamic index;cleaved caspase-1;a-HIBA;IL-18;FMA;Intestinal flora index;TMAO;IL-1ß;TNF-a;ADL;ASC;NLRP3;

Countries

China

Contacts

Public ContactMiansheng Zhu
miansheng@wanadoo.fr13398853372

Outcome results

None listed

Source: ITMCTR (via WHO ICTRP) · Data processed: Feb 4, 2026