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Blocking effect of danhuningshen Recipe on structural changes of brain dysfunction in anxiety disorder

Blocking effect of danhuningshen Recipe on structural changes of brain dysfunction in anxiety disorder

Status
Recruiting
Phases
Phase 1
Study type
Interventional
Source
ITMCTR
Registry ID
ITMCTR2200005992
Enrollment
Unknown
Registered
2022-05-11
Start date
2022-04-30
Completion date
Unknown
Last updated
2023-02-20

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Generalized anxiety disorder

Interventions

control group:Oral buspirone tablets

Sponsors

Guang'anmen Hospital,Chinese Academy of Chinese Medicine Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 79 Years

Inclusion criteria

Inclusion criteria: Inclusion criteria: ? age 18 ~ 79 years; ? Patients with generalized anxiety disorder who meet the standard; ? Meet the TCM syndrome standard of yin deficiency and internal heat syndrome; ? Stable vital signs, clear mind and certain expression ability; ? Sign informed consent and agree to participate in this study; Only those who meet the above five items can be selected.

Exclusion criteria

Exclusion criteria: ? Those who had received anti anxiety treatment within 1 week before the test; ? Refusing to take medicine (unwilling to take traditional Chinese Medicine) and having committed suicide; ? Known alcoholics or substance dependents; ? Severe insufficiency of liver and kidney function; ? Unstable vital signs ? pregnant and lactating women; If one of the above conditions is met, it will be excluded.

Design outcomes

Primary

MeasureTime frame
General clinical efficacy rating scale;5-hydroxytryptamine;Norepinephrine;dopamine;Brain functional magnetic resonance;Evaluation of curative effect of TCM Syndrome;HAMA scale;

Secondary

MeasureTime frame
Montreal cognitive function scale;

Countries

China

Contacts

Public ContactShijing Huang
gamhsj@126.com010-88001179

Outcome results

None listed

Source: ITMCTR (via WHO ICTRP) · Data processed: Feb 4, 2026