primary Sjogren's syndrome
Conditions
Interventions
healthy people group:none
patients with dry mouth or dry eyes syndrom but not diagnosised with SS group:none
Sponsors
China-Japan Friendship Hospital
Eligibility
Sex/Gender
All
Age
18 Years to 75 Years
Inclusion criteria
Inclusion criteria: Those who meet all of the following items can join the study: 1. Patients who meet 2016 ACR-EULAR Classification Criteria for primary Sjogrens Syndrome; 2. Age 18-75 years old; 3. Those who are conscious and able to communicate with others; 4. Those who signed informed consent before the start of the study, and are willing and able to complete questionnaires.
Exclusion criteria
Exclusion criteria: Those who meet one of the following items cannot be included in the study: 1. Pregnant or lactating women; 2. Mental patients; 3. Complicated with malignant tumor(s).
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Tongue images;SS-related protein expression test;Immunoglobulin (IgA, IgM, IgG)of serum;C-reactive protein(CRP);Poor prognosis(ILD, thrombocytopenia, etc.);ESSDAI score;Erythrocyte sedimentation rate(ESR);Blood mononuclear cell RNA levels of methylation;Elements of TCM syndrome; | — |
Secondary
| Measure | Time frame |
|---|---|
| Lung CT scan;ESSPRI score;Renal function test;Fatigue VAS score;Liver function test;Blood routine test;Complements;Salivary flow rate;Autoantibody;Eye dryness VAS score;Labial salivary gland histopathology;Oral dryness VAS;Ultrasound Cardiogram(UCG);Schirmer's test of both eyes;Ultrasound of lumph nodes;Pain VAS score; | — |
Countries
China
Contacts
Public ContactJing Luo
China-Japan Friendship Hospital
Outcome results
None listed