depression
Conditions
Interventions
taVNS group:taVNS?
sham taVNS group:?taVNS?
Sponsors
Guang'anmen Hospital of China Academy of Chinese Medical Sciences
Eligibility
Sex/Gender
Male
Inclusion criteria
Inclusion criteria: (1) Meet the ICD-10 classification criteria for moderate-to-mild (2 core symptoms + 2 accompanying symptoms), moderate (2 core symptoms + 3-4 accompanying symptoms) depression classification criteria; (2) The disease duration ranges from 2 weeks to 7 points in 2 years = HAMD-17 score = 24 points; (3) The age is between 18 and 70 years old, and the gender is not limited; (4) The education level is above junior high school, and can understand the content of the scale and cooperate with the research; (5) Volunteered to participate in this study and signed the informed consent.
Exclusion criteria
Exclusion criteria: (1) Patients with severe depression, or patients with severe mental illness, such as schizophrenia, mania, and those with obvious suicidal tendencies; (2) Depressive disorders caused by psychoactive substances or non-addictive substances; (3) Patients with Patients with organic brain diseases; (4) patients with serious physical diseases, such as heart disease, tumors or organic lesions of the central nervous system; (5) patients with other neurological diseases, such as epilepsy, Parkinson's disease (6) Pregnant or breastfeeding women; (7) Those with low compliance or unable to adhere to treatment for other reasons; (8) Those who are allergic to the study drug or have contraindications to fMRI scanning; (9) Those who did not sign the informed consent form.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Hamilton Anxiety Scale (HAMA-14);Hamilton Depression Scale (HAMD-17); | — |
Countries
CHINA
Contacts
Public ContactFang Jiliang
Guang'anmen Hospital, China Academy of Chinese Medical Sciences, No. 5 Beixian Pavilion, Xicheng District, Beijing
Outcome results
None listed