Bipolar disorder/Depression
Conditions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: Criteria for admission and discharge of depression ? Inclusion criteria 1) Age 18-50 years old, regardless of gender. 2) Diagnostic manual of depression (dsm-5); 3) It is consistent with the diagnosis of madness and depression syndrome in traditional Chinese medicine; 4) All vital signs are stable, with clear consciousness and certain expression ability; 5) Primary school education or above, and be able to understand the evaluation content of the scale; 6) Understand and voluntarily participate in this study. I and my family signed the informed consent form. Inclusion criteria of patients with bipolar disorder ? Inclusion criteria 1) Age 18-50 years old, regardless of gender. 2) Those who meet the diagnostic criteria of bipolar disorder in American Diagnostic and Statistical Manual of mental diseases, 5th Edition (dsm-5); 3) It is consistent with the diagnosis of madness and depression syndrome in traditional Chinese medicine; 4) All vital signs are stable, with clear consciousness and certain expression ability; 5) Primary school education or above, and be able to understand the evaluation content of the scale; 6) Understand and voluntarily participate in this study. I and my family signed the informed consent form. Admission and discharge criteria of normal control group ? Inclusion criteria 1) Diagnosed as disease-free by two deputy directors and above doctors; 2) Two lineages and three generations of relatives without history of mental illness; 3) Age and sex were matched with the other two groups; 4) All vital signs are stable, with clear consciousness and certain expression ability; 5) Primary school education or above, and be able to understand the evaluation content of the scale; 6) Understand and voluntarily participate in this study. I and my family signed the informed consent form.
Exclusion criteria
Exclusion criteria: 1) Past or present history of chronic severe physical diseases; 2) Unstable vital signs; 3) Severe aphasia, agnosia and inability to communicate; 4) Previous or present organic mental disorder, or caused by psychoactive substances and non addictive substances; 5) Combined with other types of mental disorders, such as schizophrenia; 6) The researchers considered it unsuitable for inclusion.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Hamilton Depression Scale;oung Mania Rating Scale;Positive and Negative Syndrome Scale;TCM syndrome questionnaire;Hamilton Anxiety Scale; | — |
Secondary
| Measure | Time frame |
|---|---|
| Metabonomics and other related indexes; | — |
Countries
China