suicidal ideation depression
Conditions
Interventions
Acupuncture group (Group A):acupuncture
Medication group (Group B):drug
Sponsors
Yunnan University of Chinese Medicine
Eligibility
Sex/Gender
All
Age
35 Years to 55 Years
Inclusion criteria
Inclusion criteria: 1. Suicide ideation depression subjects: (1)Right handed, han nationality, length of education = 6years (2)Men or women aged 35-55 years; (3)Meet the diagnostic criteria for DSM-V of depression; (4)Hamilton Depression Scale -24 items(HAND-24)score=20; (5)Beck Suicidal Ideation Scale rated as positive; (6)Suicidal ideation only, no experience of self-injury or suicidal behaviour (7)Those who voluntarily participate in the study, with written informed consent signed by the patient and family members, and accompanied by family members throughout the study period. 2. Healthy subjects: (1)Right handed, han nationality, length of education = 6years; (2)Men or women aged 35-55 years; (3)No history of any neurological or psychiatric disorders and family history of genetic disorders, with a HAMD-17 score <7; (4)No physical abnormalities during the trial period(e.g. flu, fever, etc.) ; (5)No drugs or alcohol for at least 2 days prior to participation in the trial, and no stimulant drug use for at least 1 month; (6)The subjects themselves signedthe informed consent.
Exclusion criteria
Exclusion criteria: 1. Suicide ideation depression subjects: (1)With bidirectional depression and other psychiatric disorders in the DSM-V diagnosis; (2)A history of self-injurious or suicidal behaviour; (3)Severe depression with unstable emotion and abnormal behaviour with difficulty in cooperating with the assessment; (4)Serious primary diseases such as cardiovascular system, liver, kidney and hematopoietic system; (5)Chronic pain(such as migraine, women with dysmenorrhea); (6)Pregnancy, lactation, or plans to become pregnant within 1 year; (7)Brain with definite organic lesions or severe asymmetry between the right and left side of the cranial structure.. (8)Nuclear magnetic contraindications (such as metal implant, vascular stents, cardiac pacemakers, false tooth, claustrophobia, etc.); (9)Has received acupuncture treatment within 6 months; (10)Has taken antidepressant or other psychotropic drugs within 6 months and with drug dependence; (11)Transsexual, homosexuality, abnormal sexual orientation, special fetishes, alcohol addict, etc. (12)Participation in a similar study in the last 3 months. 2. Healthy subjects: (1)Serious primary diseases such as cardiovascular system, brain, liver, kidney, hematopoietic system, mental disease and obvious cognitive dysfunction; (2)Chronic pain(such as migraine, women with dysmenorrhea); (3)Women during pregnancy and lactation (4)Brain with definite organic lesions or severe asymmetry between the right and left side of the cranial structure (5)Nuclear magnetic contraindications (such as metal implant, vascular stents, cardiac pacemakers, false tooth, claustrophobia, etc.); (6)Has received acupuncture treatment within 6 months; (7)Transsexual, homosexuality, abnormal sexual orientation, special fetishes, alcohol or drug abuse, etc.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Multimodal image data; | — |
Secondary
| Measure | Time frame |
|---|---|
| Clinical Global Impression;Hamilton Depression Scale -24 items;Self-rating Depression Scale;The World Health Organization Summary Quality of Life-BREF;Beck Suicidal Ideation Scale; | — |
Countries
China
Contacts
Public ContactTaipin Guo
Yunnan University of Chinese Medicine
Outcome results
None listed