coronary heart disease
Conditions
Interventions
control group:placebo on the basis of conventional therapy
treatment group:activating blood-circulation and detoxifying herbal compound
Sponsors
Xiyuan Hospital of China Academy of Chinese Medical Sciences
Eligibility
Sex/Gender
Male
Inclusion criteria
Inclusion criteria: (1)Patients with coronary artery bordeline lesions confirmed by coronary angiography or coronary computed tomographic angiography with stenosis of at least one major coronary artery lumen between 50% and 70%; (2) Patients aged 18–80 years. (3) Patients with heart function grading of NYHA grade?-? (4) Patients conform to the TCM standard of blood stasis syndrome (5) Patients will be informed about the trial and should voluntarily sign the consent form.
Exclusion criteria
Exclusion criteria: (1) Patients who had previously undergone coronary stent implantation, coronary artery bypass grafting or acute myocardial infarction within 3 months; (2) Patients with diffuse lesions throughout the diseased vessels; (3) Those who had previously undergone other cardiac operations, such as valve replacement; (4) Patients with severe heart, liver and renal insufficiency, who are not suitable for coronary angiography and related examination and treatment; (5) Persons suffering from mental disorders; (6) Persons suffering from hepatitis, tuberculosis, AIDS and other infectious diseases; (7) Allergic constitution; (8) Pregnant and lactating women; (9) Those whose life expectancy is less than one year; (10) Participated in other clinical researchers within the last 3 months.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Coronary artery calcification score;Gensini score of coronary arteri;MACE; | — |
Secondary
| Measure | Time frame |
|---|---|
| MMP-9;hs-CRP; | — |
Countries
China
Contacts
Public ContactJiang Yuerong
Outcome results
None listed