sepsis
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1. Aged more than 18 years old, less than 80 years old; 2. Patients admitted to ICU; 3. Meet the diagnostic criteria of sepsis 3.0; 4. M
Exclusion criteria
Exclusion criteria: 1. Those with contraindications to enteral nutrition such as gastrointestinal perforation, intestinal obstruction, gastrointestinal surgery and intestinal fistula; 2. AGI: Class IV; 3. The disease is endangered and the expected survival time is less than 5 days; 4. Patients with impaired immune function or undergoing immunotherapy; 5. Pregnant patients; 6. Those who are participating in other clinical trials.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Neutrophil extracellular traps, NETs;Immunological function index; | — |
Secondary
| Measure | Time frame |
|---|---|
| Time for enteral nutrition to reach standard;Enteral nutrition reached the standard on day 7;Inflammation levels;Nutrition indicators;Acute Physiology and Chronic Health Evaluation II;Sequential Organ Failure Assessment;blood test;Infection index;Intestinal mucosal permeability index;Prognostic indicators;blood test; | — |
Countries
China