severe acute pancreatitis
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: (1) Meet the diagnostic criteria of AP; (2) Meet the diagnostic criteria of Fu excess heat syndrome; (3) Meet the diagnostic criteria of predicted SAP: ? APACHE II score = 8, and/ or ? BISAP score = 3, and/ or ? Pass score > 140, and/ or ? CRP>150mg/mL. (4) Admission within 48 hours after onset (onset of abdominal pain); (5) Regardless of gender, 18-85 years old; (6) Agree to participate in this study and obtain the written informed consent of the patient or his legal representative.
Exclusion criteria
Exclusion criteria: (1) Patients with chronic pancreatitis, pancreatic tumors, or chronic serious diseases of other organ systems, as well as malignant tumors; (2) Patients with gastrointestinal perforation, gastrointestinal bleeding and complete intestinal obstruction; (3) Patients with serious condition who need non medical treatment such as surgery and peritoneal lavage; (4) Patients with a history of trauma and surgery before onset; (5) Patients who joined other clinical trials 3 months before onset; (6) Pregnancy complicated with acute pancreatitis or lactation; (7) Patients who were treated with traditional Chinese medicine before admission.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Occurrence of organ failure;Incidence of SIRS; | — |
Secondary
| Measure | Time frame |
|---|---|
| Length of stay;Symptom relief;Inflammatory index; | — |