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Effect and timing of early traditional Chinese medicine intervention in severe acute pancreatitis

Effect and timing of early traditional Chinese medicine intervention in severe acute pancreatitis

Status
Active, not recruiting
Phases
Phase 1
Study type
Interventional
Source
ITMCTR
Registry ID
ITMCTR2200005908
Enrollment
Unknown
Registered
2022-04-26
Start date
2022-04-26
Completion date
Unknown
Last updated
2023-02-20

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

severe acute pancreatitis

Interventions

Group B:Conventional treatment + Dachengqi granule treatment within the first day of admission
Group C:??????+???2?????????????
Group D:Conventional treatment + Dachengqi granule treatment within the third day of admission

Sponsors

Jinhua Municipal Central Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 85 Years

Inclusion criteria

Inclusion criteria: (1) Meet the diagnostic criteria of AP; (2) Meet the diagnostic criteria of Fu excess heat syndrome; (3) Meet the diagnostic criteria of predicted SAP: ? APACHE II score = 8, and/ or ? BISAP score = 3, and/ or ? Pass score > 140, and/ or ? CRP>150mg/mL. (4) Admission within 48 hours after onset (onset of abdominal pain); (5) Regardless of gender, 18-85 years old; (6) Agree to participate in this study and obtain the written informed consent of the patient or his legal representative.

Exclusion criteria

Exclusion criteria: (1) Patients with chronic pancreatitis, pancreatic tumors, or chronic serious diseases of other organ systems, as well as malignant tumors; (2) Patients with gastrointestinal perforation, gastrointestinal bleeding and complete intestinal obstruction; (3) Patients with serious condition who need non medical treatment such as surgery and peritoneal lavage; (4) Patients with a history of trauma and surgery before onset; (5) Patients who joined other clinical trials 3 months before onset; (6) Pregnancy complicated with acute pancreatitis or lactation; (7) Patients who were treated with traditional Chinese medicine before admission.

Design outcomes

Primary

MeasureTime frame
Occurrence of organ failure;Incidence of SIRS;

Secondary

MeasureTime frame
Length of stay;Symptom relief;Inflammatory index;

Contacts

Public ContactYi-shuang Tang
ystang19@163.com18621152537

Outcome results

None listed

Source: ITMCTR (via WHO ICTRP) · Data processed: Feb 4, 2026