ovarian reserve dysfunction
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: (1) 20 years = age < 40 years; (2) Meet the diagnostic criteria of ovarian reserve dysfunction; (3) Voluntarily participate in the trial and sign the informed consent form.
Exclusion criteria
Exclusion criteria: (1) Patients suffering from severe systemic organic diseases such as heart, liver and kidney, which makes it difficult to achieve pregnancy; (2) Combined with congenital reproductive organ development abnormalities affecting pregnancy, endometrial polyps, hysteromyomas, endometriosis, or other organic diseases. (3) Patients with polycystic ovary syndrome, hyperprolactinemia, hyperandrogenemia, hypothyroidism, chronic adrenocortical dysfunction and other diseases; (4) Severe wasting disease or developing malignant tumor; (5) Patients with bleeding tendency and prone to infection, or patients with severe allergies, or patients with skin ulcers, scars and other prohibited acupuncture; (6) IVF-ET planners are expected within 2 months after enrollment. Note: patients who meet any of the above conditions should be excluded.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| antral follicle count; | — |
Secondary
| Measure | Time frame |
|---|---|
| Peak systolic blood flow velocity;Follicle stimulating hormone;embryo implantation rate;early pregnancy loss rate;Self-Rating Anxiety Scale;Anti Mullerian hormone;?????;Clinical pregnancy rate;Luteinizing hormone;Prog;Estradiol;egg number;high-quality embryo rate;Systolic / diastolic blood flow velocity ratio;Available embryo rate;biochemical pregnancy rate;Arterial resistance index; | — |
Countries
China