chronic liver disease
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: Eligible patients with chronic liver diseases included those who were diagnosed with CHB or NAFLD, were 18–65 years of age, and signed an informed consent form.
Exclusion criteria
Exclusion criteria: Those who were diagnosed with other chronic liver diseases such as other viral hepatitis, alcoholic fatty liver disease, cirrhosis, liver cancer, and NAFLD co-infected with HBV were excluded. Those with serious primary disease or malignant tumor, who had undergone gastrointestinal bariatric surgery or taken weight loss drugs within the past three months, who had undergone gastrointestinal bariatric surgery in the past year or who had taken weight-loss drugs in the past 3 months and had lost more than 10% of their body weight, who had taken antibiotics or proton pump inhibitors within the past month, or were pregnant or lactating were also excluded. Healthy controls were defined as individuals with normal routine laboratory tests, no diagnosis of chronic liver disease, and no abnormal TCM symptoms.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| hepatitis B virus marks antibody;AFP;traditional Chinese medical syndrom;HBV-DNA;kidney function;Faecl 16sRNA;HCG;liver function index;metabonomics index;Transcriptomics index;blood glucose;Abdominal ultrasound;blood lipids; | — |
Countries
China
Contacts
IRB of Shuguang Hospital affiliated with Shanghai University of TCM