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Based on the theory of heart governs the spirit, the analysis of the correlation between heart disease and cognitive function and the study of the effect of invigorating Qi and promoting blood circulation on the intervention of stable coronary heart disease complicated with mild cognitive impairment

Based on the theory of heart governs the spirit, the analysis of the correlation between heart disease and cognitive function and the study of the effect of invigorating Qi and promoting blood circulation on the intervention of stable coronary heart disease complicated with mild cognitive impairment

Status
Active, not recruiting
Phases
Early Phase 1
Study type
Interventional
Source
ITMCTR
Registry ID
ITMCTR2200005867
Enrollment
Unknown
Registered
2022-04-15
Start date
2022-04-18
Completion date
Unknown
Last updated
2023-02-20

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

coronary heart disease

Interventions

treatment group :Xueshuanxinmaining tablet

Sponsors

Dongzhimen Hospital,Beijing University of Chinese Medicine
Lead Sponsor

Eligibility

Sex/Gender
All
Age
50 Years to 80 Years

Inclusion criteria

Inclusion criteria: ? Out-patient or inpatient patients aged 50-80 and elderly residents in the community, no gender limitation, education level =6 years; ? Patients who met the diagnostic criteria of Western medicine and Chinese medicine and had objective cognitive impairment, that is, MMSE score < 27 or cranial MRI had objective cerebral ischemia; ? No history and signs of stroke; ? Participate in the experiment voluntarily and sign the informed consent.

Exclusion criteria

Exclusion criteria: ? Patients with severe cardiac, hepatic and renal insufficiency (note: severe hepatic insufficiency refers to ALT value >2 times the upper limit of normal or AST value >2 times the upper limit of normal; Severe renal insufficiency is defined as creatinine >1.5 times the upper limit of normal); Patients with dementia or mild cognitive impairment; ? Patients with other mental and nervous system diseases and malignant tumors; (4) participants in other drug trials within three months before inclusion; ? Use of other drugs to improve cognitive function, such as ChEIs or other psychotropic drugs, within the past three months.

Design outcomes

Primary

MeasureTime frame
Cognitive function score;

Secondary

MeasureTime frame
distribution pattern of TCM syndrome;

Countries

China

Contacts

Public ContactChang Peifen
13661022016@163.com13661022016

Outcome results

None listed

Source: ITMCTR (via WHO ICTRP) · Data processed: Feb 4, 2026