coronary heart disease
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: ? Out-patient or inpatient patients aged 50-80 and elderly residents in the community, no gender limitation, education level =6 years; ? Patients who met the diagnostic criteria of Western medicine and Chinese medicine and had objective cognitive impairment, that is, MMSE score < 27 or cranial MRI had objective cerebral ischemia; ? No history and signs of stroke; ? Participate in the experiment voluntarily and sign the informed consent.
Exclusion criteria
Exclusion criteria: ? Patients with severe cardiac, hepatic and renal insufficiency (note: severe hepatic insufficiency refers to ALT value >2 times the upper limit of normal or AST value >2 times the upper limit of normal; Severe renal insufficiency is defined as creatinine >1.5 times the upper limit of normal); Patients with dementia or mild cognitive impairment; ? Patients with other mental and nervous system diseases and malignant tumors; (4) participants in other drug trials within three months before inclusion; ? Use of other drugs to improve cognitive function, such as ChEIs or other psychotropic drugs, within the past three months.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Cognitive function score; | — |
Secondary
| Measure | Time frame |
|---|---|
| distribution pattern of TCM syndrome; | — |
Countries
China