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Tanreqing capsule: a randomized, double-blind, placebo-controlled, multicenter clinical trial of efficacy and safety in the treatment of COVID-19 (mild, general)

Tanreqing capsule: a randomized, double-blind, placebo-controlled, multicenter clinical trial of efficacy and safety in the treatment of COVID-19 (mild, general)

Status
Recruiting
Phases
Phase 4
Study type
Interventional
Source
ITMCTR
Registry ID
ITMCTR2200005859
Enrollment
Unknown
Registered
2022-04-13
Start date
2022-03-30
Completion date
Unknown
Last updated
2023-02-20

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Novel coronavirus Pneumonia (COVID-19)

Interventions

Control group:Basic medication: Vitamin C effervescent tablets , 1g, QD, taken after brewing with warm boiled water, basic treatment + placebo, 3 tablets/time, 3 times a day, specification 0.4g×9 tabl
experimental group:Basic medication: Vitamin C effervescent tablet , 1g, QD, take after brewing with warm water, basic treatment + Tanreqing capsule, 3 tablets/time, 3 times a day, specification 0.4g×

Sponsors

Ruijin Hospital affiliated to Shanghai Jiaotong University School of Medicine (North Hospital)
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 75 Years

Inclusion criteria

Inclusion criteria: (1) Those who conform to the diagnosis of novel coronavirus pneumonia according to the Novel Coronavirus Diagnosis and Treatment Protocol for Pneumonia (Trial Edition 9) and are clinically classified as mild or ordinary type; (2) Aged between 18 and 75, with no gender limitation; (3) Voluntarily accept the drug treatment and sign the informed consent.

Exclusion criteria

Exclusion criteria: (1) Patients with severe primary respiratory diseases or other pathogenic microbial pneumonia that needs to be differentiated from COVID-19; (2) immune deficiency disease, or use of immunosuppressants or glucocorticoids in the last 3 months; (3) pregnant and lactating women; (4) People with allergic constitution (allergic to more than two drugs or food or known allergic to the drug used in this study); (5) mentally ill persons or persons without self-awareness; (6) Patients whose expected survival time from screening is not more than 48 hours; (7) those who have been intubated or mechanically ventilated at the time of screening; (8) In patients with serious primary diseases of heart, brain, liver and kidney, ALT and AST were 1.5 times higher than the upper limit of normal value; (9) Other conditions that the investigator considers inappropriate for clinical trial participation.

Design outcomes

Primary

MeasureTime frame
Improvement of major symptoms of COVID-19;

Secondary

MeasureTime frame
Ct values of N gene and ORF gene were detected by novel Coronavirus nucleic acid ;Turn to weight ratio ;

Countries

China

Contacts

Public ContactZhao Ren
1217909635@qq.com+86 025 86802480

Outcome results

None listed

Source: ITMCTR (via WHO ICTRP) · Data processed: Feb 4, 2026