Bipolar disorder
Conditions
Interventions
medicine:Quetiapine
traditional Chinese medicine:Traditional Chinese medicine granule preparation
Sponsors
Beijing Anding Hospital, Capital Medical University
Eligibility
Sex/Gender
All
Age
18 Years to 55 Years
Inclusion criteria
Inclusion criteria: ? The diagnosis of bipolar disorder was evaluated by structured clinical interview for DSM-IV Axis I disorders (SCID-I / P). Bipolar disorder was diagnosed according to DSM-IV diagnostic criteria and is currently a depressive episode; ? Age 18-40 years; ? 24 items Hamilton Depression Scale (hamd-24) = 20 points, = 35 points (lasting for 2 weeks), and Hamilton Anxiety Scale (HAMA) = 7 points (lasting for more than 2 weeks); Young manic Rating Scale (YMRS) = 5 points; ? Meet the diagnostic criteria of fire heat syndrome; ? Junior high school education or above; ? No somatic diseases and endocrine diseases; ? Have sufficient audio-visual level to complete the examination necessary for the study; ? The patient and his guardian agreed and signed the informed consent form.
Exclusion criteria
Exclusion criteria: ? The possibility of bipolar depression caused by somatic diseases and endocrine diseases; ? The possibility of bipolar depression caused by psychoactive substances; ? Accompanied by other mental diseases, such as anxiety, schizophrenia, manic episode, obsessive-compulsive disorder, etc; ? Patients with unstable vital signs and serious suicidal concept; ? Women breastfeeding, pregnant or preparing for pregnancy; ? Alcohol and drug dependence within 1 year; ? Those with a history of severe drug allergy; ? Those who have participated in clinical trials of other drugs within 30 days; ? Patients who had taken monoamine oxidase inhibitors within 4 weeks before enrollment, or patients treated with long-acting mental blockers, or patients receiving hormone drugs
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Hamilton Depression Scale;Syndrome integral of internal depression of fire heat in traditional Chinese Medicine; | — |
Secondary
| Measure | Time frame |
|---|---|
| Clinical Global Impression;Hamilton Anxiety Scale; | — |
Countries
China
Contacts
Public ContactDongqing Yin
Outcome results
None listed