Multiple Myeloma Causes Peripheral Neuropathy
Conditions
Interventions
Treatment group:midnight-noon ebb-flow acupuncture and Mecobalamin
Sponsors
Zhabei Central Hospital in Shanghai Jing'an District
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: Inclusion criteria: 1. Patients diagnosed with MM; 2. Patients without PN at baseline, those experiencing PN grade 2 or above after Bortezomib chemotherapy (the severity of neuropathy was evaluated according to NCI CTCAE, version 3.0); Electromyography examination suggesting conduction disorders of the median and peroneal nerves, slowing down of one item or more items of NCV; 3. Willing to terminate chemotherapy for three months and receive treatment using this method; Patients who signed informed consent.
Exclusion criteria
Exclusion criteria: Exclusion criteria: 1. Patients who were pregnant; 2. Those with severe heart, liver, and kidney dysfunction or other critical diseases (such as malignant tumors); 3. Those with PN caused by reasons other than chemotherapy, such as plasma cell tumor compression, nutritional disorders, and infection; 4. Those with platelet count < 30 × 109/L and white blood cell count < 3.0 × 109/L before the treatment; 5. Patients who were unable to communicate due to severe cognitive disorder; 6. Those who did not cooperate or refused to sign informed consent.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| TCSS;M protein; | — |
Secondary
| Measure | Time frame |
|---|---|
| conduction velocity of median nerve and common scarlet nerve;Average number of bone marrow plasma cells;Mean hemoglobin; | — |
Countries
China
Contacts
Public Contactzhoufan
Outcome results
None listed