Kidney-essence deficiency patients, premature aging population
Conditions
Interventions
control group:Bazi Bushen capsule placebo
therapy group:Bazi Bushen Capsule
Sponsors
Xiyuan Hospital, Chinese Academy of Chinese Medical Sciences
Eligibility
Sex/Gender
All
Age
30 Years to 80 Years
Inclusion criteria
Inclusion criteria: 1. Meet the diagnostic criteria of traditional Chinese medicine for kidney-essence deficiency syndrome; 2. The performance score of the core symptom aging evaluation scale of TCM kidney-essence deficiency syndrome =10 points; 3. Age =30 years old and =80 years old, male or female; 4. Voluntarily participate in this study and sign the written informed consent.
Exclusion criteria
Exclusion criteria: Overall Exclusion Criteria: 1. Those with severe disease or unstable disease state caused by age-related changes of important organs; 2. Patients with severe liver and kidney insufficiency, malignant tumors, blood diseases and other system diseases such as circulation, respiration, nerve (moderate and severe PD/AD); 3. Those with severe mental illness or cognitive dysfunction; 4. Persons with physical disabilities; 5. Those who meet the diagnostic criteria of liver-yang hyperactivity syndrome, excess heat syndrome, damp-heat syndrome, and internal heat syndrome due to yin deficiency, or those who normally meet the above constitutions; 6. Screen patients with a history of alcohol or drug abuse within 1 year before enrollment; 7. Screen those who participated in clinical trials of other drugs within 1 month before enrollment; 8. Known or suspected to have a history of allergy or allergic constitution to the test drug and its excipients; 9. Pregnant or breastfeeding female patients; 10. Patients deemed unsuitable for participation in the study by the investigator due to possible violation of the trial protocol or any other circumstances affecting its safety.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Changes in Chinese version of Tilburg Frailty Assessment Scale (TFI) scores after 12 weeks of treatment;Changes in the core symptom aging evaluation scale of traditional Chinese medicine kidney-essence deficiency syndrome after 12 weeks of treatment; | — |
Secondary
| Measure | Time frame |
|---|---|
| 5 sitting times, 6-minute walking distance, etc;scalp;Motor function test;skin;Hair;Computer face recognition age;Serum sex hormone level and other indicators;Quality of life rating scale (SF-36);Peripheral blood aging markers; | — |
Countries
China
Contacts
Public ContactFengqin Xu
Outcome results
None listed