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Clinical effect and mechanism of acupuncture-assisted methadone dose reduction in MMT patients

Clinical effect and mechanism of acupuncture-assisted methadone dose reduction in MMT patients

Status
Active, not recruiting
Phases
Early Phase 1
Study type
Interventional
Source
ITMCTR
Registry ID
ITMCTR2200005787
Enrollment
Unknown
Registered
2022-03-30
Start date
2022-04-12
Completion date
Unknown
Last updated
2023-02-20

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

opioid use disorder

Interventions

sham acupuncture group:sham acupuncture
acupuncture group:acupuncture

Sponsors

Guangzhou University of Chinese Medicine
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: (1) Meet the diagnostic criteria for opioid use disorder in the American Psychiatric Association's Diagnostic and Statistical Manual of Mental Disorders, Fifth Edition (DSM-V). Diagnostic criteria; (2) 18 to 60 years old; (3) Currently receiving methadone maintenance therapy for at least 6 weeks; (4) A need for methadone reduction; (5) No acupuncture treatment in the past 3 months; (6) Sign the informed consent.

Exclusion criteria

Exclusion criteria: Any of the following is excluded: (1) Patients with severe heart, liver, spleen, lung, and kidney diseases; (2) Combined with severe digestive system diseases and severe malnutrition; (3) People with AIDS or syphilis; (4) Patients with severe primary diseases of the hematopoietic system; (5) Those who have inflammation, scars, or trauma at the operation site, or those who have other serious systemic infections; (6) Those with a history of mental illness and language and communication disorders; (7) Pregnant women or those planning to become pregnant; (8) Those who cannot cooperate or are participating in drug trials.

Design outcomes

Primary

MeasureTime frame
Clinical Opiate Withdrawal Scale;effective rate of MMT reduction;

Secondary

MeasureTime frame
Pittsburgh sleep quality index;Visual Analogue Scales;Beck Anxiety Inventory;Beck Depression InventoryII-II;Urine morphine test;

Countries

China

Contacts

Public ContactLu Liming
lulimingleon@126.com13751779800

Outcome results

None listed

Source: ITMCTR (via WHO ICTRP) · Data processed: Feb 4, 2026