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Based on HSP70/NF-?B/Caspase3 signaling pathway to explore the clinical mechanism of Cangfu Daotan Prescription in patients with phlegm-dampness polycystic ovary syndrome

Study on TCM Syndrome of Phlegm-Dampness PCOS Infertility Based on Follicular Fluid Proteomics

Status
Active, not recruiting
Phases
Early Phase 1
Study type
Interventional
Source
ITMCTR
Registry ID
ITMCTR2200005785
Enrollment
Unknown
Registered
2022-03-30
Start date
2022-04-01
Completion date
Unknown
Last updated
2023-02-20

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Polycystic ovary syndrome

Interventions

three:the placebo
one:Cangfu phlegm guide soup intervention
two:the placebo

Sponsors

Affiliated Hospital of Shandong University of Traditional Chinese Medicine
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
25 Years to 35 Years

Inclusion criteria

Inclusion criteria: ? It conforms to the diagnostic criteria of traditional Chinese and Western medicine ? Body mass index (BMI) was greater than 25kg/m2 ?20= age =35 years ? No hormone drugs were used in the first three months of treatment ? Sign relevant informed consent ? Approved by the Ethics Committee ? In line with the "Human Assisted Reproductive Technology Specifications"

Exclusion criteria

Exclusion criteria: ? Those who do not follow the doctor's advice or are allergic to the Chinese medicine ingredients ? Complicated with endometriosis, adenomyosis, ovarian tumor, decreased ovarian reserve function, pelvic inflammatory disease and other systemic diseases affecting ovarian function ? Infertility caused by genetic factors (4) a history of recurrent abortion ? Abnormal anatomical structure of female reproductive tract does not have pregnancy function ? The woman suffers from serious physical or mental disease and cannot bear pregnancy

Design outcomes

Primary

MeasureTime frame
I?Ba;NF-?B;Heat shock protein 70;Caspase-3;

Secondary

MeasureTime frame
Clinical pregnancy rate;Optimal rate of embryo;Ratio of the egg;A number of eggs;

Countries

China

Contacts

Public ContactLian Fang
lianfangbangong@163.com13706403122

Outcome results

None listed

Source: ITMCTR (via WHO ICTRP) · Data processed: Feb 4, 2026