hyperuricemia patients
Conditions
Interventions
The control group:Oral febuxostat treatment+ Lifestyle adjustment (diet, exercise)
The experimental group:Oral invigorating spleen and removing dampness prescription+ Lifestyle adjustment (diet, exercise)
Sponsors
Department of Immunity,the Tianjin FirstHospital,Tianjin,
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: The standard age was 18-65 years old, with no gender limitation.The inclusion criteria met the diagnostic criteria set by Multidisciplinary Expert Consensus on diagnosis and Treatment of Hyperuricemia Related Diseases in China (2017) : for both men and women, fasting uric acid level exceeded 420µmol/L, which was called hyperuricemia.
Exclusion criteria
Exclusion criteria: Secondary gout caused by kidney disease, blood disease, taking drugs, tumor radiation and chemotherapy, etc. In the acute onset of gouty arthritis; Caused by rheumatoid arthritis, psoriatic arthritis, bone tumors and other joint lesions; With serious pulmonary, cardiovascular, hematopoietic, central nervous system or other systemic diseases; Complicated with malignant tumor; Glutamic-pyruvic transaminase or glutamic-oxalacetic transaminase was 1.5 times higher than the upper limit of normal range; Serum creatinine was higher than the upper limit of normal range; Had undergone sex hormone replacement therapy and oral contraception in the past 3 months; Taking more than 10 mg/d of prednisone or other equivalent glucocorticoids; Or failing to take medication as prescribed. Pregnant or breast-feeding women or those who plan to become pregnant; Allergic to test drugs, weak physique or allergic constitution: those who meet any one of the above criteria can be excluded from the study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The level of TNF-?;IL-1ß;Blood uric acid; | — |
Secondary
| Measure | Time frame |
|---|---|
| Number of new episodes of hematuria soreness and wind during each visit;renal function;C-reactive protein;Blood sedimentation;Liver function; | — |
Countries
china
Contacts
Public ContactChunye Wu
Outcome results
None listed