colorectal cancer
Conditions
Interventions
Control group:Oxaliplatin+Capecitabine
Experiment group:Oxaliplatin+Capecitabine+Yiqi Chupi powder
Sponsors
Shanxi Province Hospital of Traditional Chinese Medicine
Eligibility
Sex/Gender
All
Age
18 Years to 80 Years
Inclusion criteria
Inclusion criteria: 1.The pathological examination conforms to the diagnostic criteria of western medicine for colorectal cancer; 2.Postoperative stage of colorectal cancer is stage II with high-risk factors; or postoperative stage is stage III and requires postoperative adjuvant chemotherapy. 3.Comply with the diagnostic criteria of TCM syndrome of qi deficiency and kidney deficiency; 4.Age between 18-80 years old, no gender restrictions; 5.Liver and kidney function and hematopoietic function are basically normal(in the absence of ongoing supportive care):Neutrophils>1.5×109/L, platelets>100×109/L, hemoglobin>9.0g/dL; total bilirubin normal or <1.5×ULN; AST(SGOT), ALT(SGPT) <2.5×ULN ; Serum creatinine <1.5×ULN; 6.Expected survival = 6 months; 7.The score of KPS=60 points; 8.Signing the informed consent voluntarily .
Exclusion criteria
Exclusion criteria: 1.Patients who have mental disorders (mental disorders or severe dementia); 2.Liver and kidney functions are abnormal(AST, ALT, TBIL values are higher than 2.5 times the upper limit of normal values or BUN, Cr values are higher than 2 times the upper limit of normal values), Cardiac enzyme abnormalities(CK or CK-MB values above the upper limit of normal); Blood routine is abnormal(WBC, HGB, PLT are lower than the normal); 3.The patients who combined with other serious circulatory system, hematopoietic system, digestive system, endocrine system and other diseases; 4.Those who refuse postoperative adjuvant chemotherapy; 5.Pregnant, breastfeeding and planning to become pregnant; 6.He people participated in other clinical research in the past 1 month.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Piper Fatigue Score; | — |
Secondary
| Measure | Time frame |
|---|---|
| Disease Free Survival;C reactive protein;Tumor markers;The score of troditional Chinese medicine syndrome;The score of Karnofsky; | — |
Countries
China
Contacts
Public ContactShulan Hao
Outcome results
None listed