recurrent implantation failure
Conditions
Interventions
Blank control group:No extra intervention
Sponsors
Chengdu Xinan Gynecological Hospital
Eligibility
Sex/Gender
Female
Age
22 Years to 40 Years
Inclusion criteria
Inclusion criteria: (1) Aged between 22 to 40 female. (2) Meeting the diagnostic criteria for recurrent implantation failure. (3) The availability of frozen embryos and prepare for FET . (4) Patients undergoing endometrial preparation using a hormone replacement therapy or Gnrh-a down regulation hormone replacement therapy. (5)Patients with endometrial flow type II or type I. (6) Signed an informed consent form. Note: Patients meeting all 6 criteria above were included in this study.
Exclusion criteria
Exclusion criteria: (1) Ultrasound examination shows unaddressed uterine malformations that clearly affect uterine morphology, uterine fibroids that compress the uterine cavity, or ovarian cysts (2) Having a clearly diagnosis autoimmune disease or pre-thrombotic state, such as systemic lupus erythematosus, rheumatoid arthritis, etc. (3) Having an unsolved endocrine disorder, such as hyperthyroidism, diabetes mellitus, hypertension, etc. (4) Suffering from a clearly diagnosed medical or surgical serious primary or secondary disease or psychiatric disorder in progress. (5) Patients with chromosomal abnormalities(Except for chromosome polymorphism). (6) The patient has a history of assisted reproduction live births (7) Patients with bleeding tendencies and those prone to infection, or those suffering from severe allergies, or with skin ulcers or scarring that prohibit needling or dizziness. (8) Patients who have received acupuncture treatment in the last three months. (9) Patients who are participating in other clinical trials. Note: Anyone who meets any 1 of the above criteria will be excluded.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Endometrial volume blood flow; | — |
Secondary
| Measure | Time frame |
|---|---|
| Endometrial pattern;Clinical pregnancy rat;Tension assessment of VAS scale;Endometrial thickness;MV-Flow ovarian vascular index;MV-Flow endometrial vascular index;Deiqi scale of acupuncture treatment;Uterine artery index;Endometrial volume;Endometrial blood flow pattern;Embryo implantation rate; | — |
Countries
China
Contacts
Public ContactYang Jie
Outcome results
None listed