Gastroesophageal Reflux Disease
Conditions
Interventions
Treatment group:Sodium Rabeprazole Enteric-coated Tablets
Treatment group:Tongjiangjieyu decoction
Sponsors
Guang'anmen Hospital, China Academy of Chinese Medical Sciences
Eligibility
Sex/Gender
All
Age
18 Years to 80 Years
Inclusion criteria
Inclusion criteria: ?Meet the diagnostic criteria of Western medicine and traditional Chinese medicine for GERD; ?Age from 18 to 80 years old, gender is not limited; ?Sign informed consent; ?No GERD-related drug treatment within the past 1 month.
Exclusion criteria
Exclusion criteria: ? Patients with peptic ulcer, history of esophagus and/or gastric surgery, malignant lesions, Zollinger-Ellison syndrome, achalasia and other primary esophageal motility diseases, physical and chemical esophageal mucosal damage, and pyloric obstruction; ? Combined Patients with severe cardiopulmonary disease, endocrine, connective tissue disease and extra-digestive tract malignant tumor, the liver and kidney function tests were performed in the past 1 year, and the indicators were abnormal and clinically significant; ? Pregnant, planned pregnancy and lactating women; ?Patients who are allergic to drug ingredients; ? Those who have participated in other clinical trials within the past 1 month.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| GERD Q score; | — |
Secondary
| Measure | Time frame |
|---|---|
| RSI score;HADS score;Serum inflammatory factor levels;Traditional Chinese Medicine symptom score; | — |
Countries
China
Contacts
Public ContactLiu Zhen
Outcome results
None listed