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Effect of serum on fibroblasts and macrophages in patients with primary liver cancer before and after TACE and the effect of Jiedu recipe

Effect of serum on fibroblasts and macrophages in patients with primary liver cancer before and after TACE and the effect of Jiedu recipe

Status
Active, not recruiting
Phases
Early Phase 1
Study type
Interventional
Source
ITMCTR
Registry ID
ITMCTR2200005664
Enrollment
Unknown
Registered
2022-02-27
Start date
2022-04-01
Completion date
Unknown
Last updated
2023-02-20

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Primary liver cancer

Interventions

Trial Group:TACE combine with Jiedu recipe

Sponsors

Shanghai Changhai Hospital
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: (1) Patients with primary liver cancer diagnosed according to the diagnostic and therapeutic specifications for primary liver cancer (2019 Edition) are classified as stage B in Barcelona; (2) Patients should not receive any Chinese herbal medicine and systemic treatment in the past two weeks; (3) ECoG (Eastern Cooperative Oncology Group) score 0-1; (4) Compensatory liver function, or child Pugh grade A or B; (5) Patients need a life expectancy of at least 3 months; (6) Voluntarily accept the treatment of this study protocol and sign the informed consent form.

Exclusion criteria

Exclusion criteria: (1) Taking drugs that may affect the evaluation observation indexes during the trial; (2) The child Pugh score of liver function was grade C; (3) WBC < 2.0 × 10 ^ 9 / L, platelet < 30 × 10^9/L (4) Tumors accounted for more than 70% of the whole liver; (5) Patients with serious primary diseases such as cardio cerebrovascular, liver, kidney and hematopoietic system and psychosis; (6) Those who fail to take drugs according to the regulations after informed consent, cannot judge the curative effect, or incomplete data affect the judgment of curative effect.

Design outcomes

Primary

MeasureTime frame
PFS;

Countries

China

Contacts

Public ContactShufang Liang
929674871@qq.com15026971980

Outcome results

None listed

Source: ITMCTR (via WHO ICTRP) · Data processed: Feb 4, 2026