polycystic ovary syndrome
Conditions
Interventions
control group:Metformin
intervention group:Metformin + acupoint injection
Sponsors
Chongqing Traditional Chinese Medicine Hospital
Eligibility
Sex/Gender
Female
Age
18 Years to 40 Years
Inclusion criteria
Inclusion criteria: ? Meet the recommendations of the expert meeting of the European Society for human reproduction and embryo and American Society of reproductive medicine (ESHRE / ASRM) in Rotterdam in 2003; ? 18-40 years old; ? Having no intention of pregnancy, taking non-drug contraceptive measures (male using condom) after selection; ? Those who can follow up according to the experimental requirements
Exclusion criteria
Exclusion criteria: ? Persons over 40 years old or under 18 years old; ? Long term or recent application of exogenous androgen; Or being treated with corticosteroids; Or receiving malignant tumor treatment; Or have a history of drug abuse and alcoholism in the past 2 years; ? Those who have used metformin or other insulin sensitizers in the past 1 month; ? Combined with other endocrine diseases: such as hyperprolactinemia, thyroid disease, androgen secreting tumor, Cushing's syndrome, congenital adrenal cortical hyperplasia, etc; ? Those with serious cardiovascular, blood, liver and kidney diseases and low immune function; ALT or AST is higher than the upper limit of normal reference value, and serum creatinine is higher than the upper limit of normal reference value; ? Patients who cannot take effective contraceptive measures during the experiment; ? Patients with other infertility diseases besides PCOS; ? Pregnant and lactating women; ? Patients with a history of mental illness or active mental illness
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| HOMA-IR; | — |
Secondary
| Measure | Time frame |
|---|---|
| ß-cell function;Plasma lilpid;weight;Plasma glucose;sex hormones;waist;Plasma insulin;HbA1c; | — |
Countries
China
Contacts
Public ContactWu Jinlin
Outcome results
None listed