stable angina
Conditions
Interventions
Health group:no
Treatment group:Lingbao Huxin Pill + Conventional Western Medicine
Group of acute myocardial infarction:no
Sponsors
Shuguang Hospital of Shanghai University of Traditional Chinese Medicine
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1.Inclusion criteria for the stable angina group (1) Meet the western medical diagnostic standards for stable type angina of coronary heart disease; (2) Meet the TCM dialectical standards for qi deficiency and blood stasis; (3) Patients with angina attacks 2 or more times a week; (4) The Canadian Cardiovascular Society (CCS) graded angina with gradeS I.-III.; (5) Age 18-80 years old (including 18 and 80 years old); (6) Sign the informed consent form. 2.Criteria for inclusion in the acute myocardial infarction group (1) Meet the diagnostic criteria of Western medicine for acute myocardial infarction; (2) Meet the TCM dialectical standards for qi deficiency and blood stasis; (3) The onset time is less than 6 hours, and the coronary angiography is confirmed by emergency coronary angiography to confirm the single, double or triple vascular lesions of the coronary arteries and PCI; (4) Age 18-80 years old (including 18 and 80 years old); (5) Sign an informed consent form. 3.Inclusion criteria for health groups (1) Determined to be in good health by the Physical Examination Center of Shuguang Hospital; (2) Meet the physical and mental health standards determined by the WHO; (3) Age 18-80 years old (including 18 and 80 years old); (4) Sign the informed consent form.
Exclusion criteria
Exclusion criteria: (1) Pregnant, planned pregnancy or lactating women; (2) Those with serious cardiovascular diseases such as refractory heart failure, cardiogenic shock, and severe valvular heart disease; (3) Chest pain caused by lesions other than coronary artery disease, such as psychosis, severe neurosis, hyperthyroidism, biliary syndrome, gastric and esophageal reflux, aortic dissection, etc.; (4) Complicated with uncontrolled grade III hypertension (systolic blood pressure = 180mmHg and/or diastolic blood pressure =110mmHg), severe arrhythmias; (5) Severe respiratory diseases such as severe pulmonary insufficiency (PaO2<60mmHg). (6) Patients with severe liver and kidney diseases such as hepatic insufficiency (the level of alanine aminotransferase or aspartate aminotransferase is more than 2 times higher than normal), renal insufficiency (creatinine level is more than 2 times higher than normal); (7) There are other serious diseases or conditions such as malignant tumors, severe anemia, and severe renal artery stenosis; (8) Patients who are allergic to the components of the test drug and have severe allergic constitutions; (9) Those who have participated in clinical research of other drugs in the past 2 months; (10) Recently, researchers with infections, traumas, etc. have judged that they cannot participate in the study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| TCM syndrome score; | — |
Secondary
| Measure | Time frame |
|---|---|
| Blood metabolites;Grading of angina;Seattle Angina Scale score;Low density lipoprotein cholesterol;Superoxide dismutase;Echocardiography;Angina symptom score;electrocardiogram;high-density lipoprotein cholesterol;nitric oxide;Hypersensitive C-reactive protein;major adverse cardiovascular event;Triglycerides;Fasting blood glucose;Total cholesterol; | — |
Countries
China
Contacts
Public ContactXiaolong Wang
Outcome results
None listed