Polycystic Ovary Syndrome
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1. Phlegm-damp type PCOS patients ?In line with the diagnostic criteria of Chinese and Western medicine for phlegm-damp PCOS; ?Body Mass Index (BMI) = 27kg/m2; ?Age between 20 and 35 years old; ?Have signed the informed consent. 2. Non-phlegm-damp PCOS patients ?Comply with the western medicine diagnostic standards of PCOS; ? BMI is 18~26kg/m2; ?Age between 20 and 35 years old; ?Have signed the informed consent. 3. Normal control group patients ? Those who practice assisted reproductive technology due to male factors; ?BMI is 18~26kg/m2; ?Age between 20 and 35 years old; ?Have signed the informed consent.
Exclusion criteria
Exclusion criteria: 1. Age 35 years old; 2. Suffering from other diseases that can cause ovulation disorders or hyperandrogenism, such as hyperprolactinemia, Cushing's syndrome, congenital adrenal hyperplasia, etc.; 3. Combined with other systemic diseases and inflammatory diseases, such as diabetes, hyperthyroidism, heart disease, etc.; 4. Those with a history of recurrent miscarriage;
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| caspase-1;apoptosis - associatedspeck-like protein containing a CARD(ASC);IL-18;IL-1b;pyrin domain containing 3 (NLRP3);NEK7; | — |
Secondary
| Measure | Time frame |
|---|---|
| Body Mass Index(BMI);anti-Müllerian hormone(AMH);Luteinizing hormone(LH);follicle stimulating hormone(FSH);testosterone(T); | — |
Countries
China