Depression
Conditions
Interventions
Acupuncture group:Acupuncture
Sham Acupuncture group:Sham Acupuncture
Sponsors
The Second Affiliated Hospital of Zhejiang Chinese Medicine University
Eligibility
Sex/Gender
All
Age
12 Years to 18 Years
Inclusion criteria
Inclusion criteria: Patients who met the above diagnostic criteria; aged 12-18 years; conscious, with stable vital signs and some expressiveness; patients with mild to moderate depression with a Hamilton Depression Scale (HAMD) score between 20-35; and those who agreed to sign the informed consent form after approval by the ethics committee of the hospital.
Exclusion criteria
Exclusion criteria: Patients with secondary depression caused by other organic pathologies; those with severe heart, liver, lung or kidney dysfunction or serious diseases and those with infectious diseases; adolescent females in pregnancy or breastfeeding; those taking antibiotics, steroids, immunosuppressants, etc. 2 weeks prior to the assessment; those with severe suicidal self-abusive tendencies.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| HAMD;ALFF\ReHo\FC;SDS;BDI-II;intestinal microbial communities; | — |
Secondary
| Measure | Time frame |
|---|---|
| GABA;SCFAs;5-HT;CORT;NE;BDNF;DA; | — |
Countries
China
Contacts
Public ContactJiang Jinlan
Outcome results
None listed