Decrease in immune function
Conditions
Interventions
Placebo group:Take placebo orally, 3 capsules, twice a day, for 12 weeks
Experimental group:Take Zhenyuan capsule orally, 3 capsules, twice a day, for 12 weeks
Sponsors
Xiyuan Hospital ,China Academy of Chinese Medical Sciences
Eligibility
Sex/Gender
All
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: (1) 18-65 years old. (2) Persons with weak constitution and easy to get sick (1 of them can be satisfied) ? =5 common colds per year; ? acute trachea-bronchitis/pneumonia caused by infection =2 times per year (except bronchitis/pneumonia caused by infectious disease); ? =5 episodes of acute diarrhoea per year (excluding diarrhoea caused by food intolerance). (3)Meet the standard of spleen and kidney deficiency syndrome of TCM Primary symptom: fatigue, waist knee acerbity. Secondary symptoms: shortness of breath, lazy speech, loose stools ? hair loss, forgetfulness, loss of sexual desire; the pale tongue or The tongue is pale and fat with teeth marks, thin white moss, slow or weak pulse. Two primary symptomsor one main syndrome plus each one of secondary syndrome ? and ?, combined with tongue and pulse can be determined as deficiency of spleen and kidney syndrome. (4)Voluntarily sign informed consent.
Exclusion criteria
Exclusion criteria: (1) Patients with immune-related diseases and tumors. (2) Decreased immune function caused by taking drugs. (3) Allergic to multiple drugs or the known components of the study product. (4) The couple who have pregnancy plan within half a year, pregnancy or breast-feeding women. (5) Patients with serious diseases of heart, brain, liver, kidney and hematopoietic system, serious occupational diseases and mental diseases. (6) Taking drugs, nutrients, probiotics and tonic Chinese medicines which affecting immune function 4 weeks before the start of the trial will affect the judgment of the results.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Symptom Score scale;the MOS item short from health survey, SF-36; | — |
Secondary
| Measure | Time frame |
|---|---|
| Humoral immunity 7;T cell subsets; | — |
Countries
China
Contacts
Public ContactKou Qiuai
Outcome results
None listed