Irritable bowel syndrome
Conditions
Interventions
back-shu point group:back-shu point acupuncture
healthy subjects not randomization:no intervention
front-mu point group:front--mu point acupuncture
back-shu points and front-mu points combination group:back-shu points and front-mu points combination acupuncture
Sponsors
the Second Affiliated Hospital of Anhui University of Chinese Medicine
Eligibility
Sex/Gender
All
Age
20 Years to 60 Years
Inclusion criteria
Inclusion criteria: Included in the standard (1) Roman ? diagnostic criteria; (2) 20-60 years old; (3) The course of disease is more than 6 months; (4) HAMA score is 7 or above; (5) Unexplained symptoms of structural abnormalities and physiological and pathological abnormalities; (6) No metal implants in the body, and no contraindications of fMRI detection; (7) Have not used any IBS drugs (except for emergency treatment) for at least 2 weeks before the initiation of treatment, have not received acupuncture treatment for IBS in the recent 3 months, and have not participated in other ongoing clinical investigators; (8) Have not received formal psychological treatment or psychiatric drug treatment, and have not used any psychotropic drugs in recent 2 weeks; (9) right-handed; (10) The subject signed the informed consent and voluntarily participated in the study; Note: Patients who meet the above 10 criteria at the same time can be included in this study.
Exclusion criteria
Exclusion criteria: Exclusion criteria (1) have intestinal organic lesions (such as ulcerative colitis, Crohn's disease), or systemic diseases affecting digestive tract motility (such as advanced thyroid function, hypopituitary function, systemic lupus erythematosus, alcoholic liver disease, etc.); (2) patients with serious primary diseases such as cardiovascular system, digestive system, hematopoietic system, mental system, liver and kidney; (3) have a history of abdominal or rectoanal surgery; (4) people who regularly take drugs that affect gastrointestinal motility or change intestinal flora; (5) during pregnancy, lactation, postpartum years and allergic constitution; (6) Patients with severe anxiety whose HAMA score =29; (7) Those who have a history of headache or brain trauma, or have a history of dependence on psychoactive substances such as alcohol, or have obvious intellectual disabilities; (8) Subjects with claustrophobia and other contraindications; (9) Severe anatomical asymmetry of the skull or definite lesions found in the scan; (10) Unable to cooperate with the completion of this study. Note: Patients who meet any of the above criteria are excluded.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Resting state fMRI scan; | — |
Countries
China
Contacts
Public ContactCaifeng Zhu
Outcome results
None listed