A randomized controlled trial of Cooling Blood Removing Toxic Materials prescription in the treatment of erosive oral lichen planus

Status

Active, not recruiting

Phases

Early Phase 1

Study type

Interventional

Source

ITMCTR

Registry ID

ITMCTR2200005541

Enrollment

Unknown

Registered

2022-01-16

Start date

2022-02-01

Completion date

Unknown

Last updated

2023-02-20

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

oral lichen planus

Interventions

Control group:Tacrolimus + placebo

Test group:Tacrolimus + Cooling Blood Removing Toxic Materials prescription

Eligibility

Sex/Gender

All

Age

18 Years to 80 Years

Inclusion criteria

Inclusion criteria: 1) It meets the diagnostic criteria of erosive oral lichen planus; 2) informed consent to participate in the clinical trial; 3) At least 18 years of age.

Exclusion criteria

Exclusion criteria: 1) Patients with burning mouth syndrome, discoid lupus erythematosus or leukoplakia and other oral mucosal diseases; 2) Patients with autoimmune diseases such as systemic lupus erythematosus, rheumatoid arthritis and Sjogren's syndrome; 3) Patients with serious systemic diseases and tumors; 4) Previous history of adrenocortical dysfunction; 5) Long term or recent use of glucocorticoids or immunosuppressants, use of antidepressants, anti anxiety drugs or oral contraceptives; 6) Some drugs or amalgam fillings may cause mossy like reactions; 7) Recent history of mental illness; 8) Pregnant and lactating women.

Design outcomes

Primary

Measure	Time frame
symptom;	—

Countries

China

Contacts

Public ContactDai Zhong

dzdaizhong@aliyun.com+8613161080062

Outcome results

None listed

Source: ITMCTR (via WHO ICTRP) · Data processed: Feb 4, 2026