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Study on biological basis of damp heat syndrome of glycolipid metabolic diseases

Study on biological basis of damp heat syndrome of glycolipid metabolic diseases

Status
Active, not recruiting
Phases
Phase 4
Study type
Observational
Source
ITMCTR
Registry ID
ITMCTR2200005531
Enrollment
Unknown
Registered
2022-01-11
Start date
2022-01-11
Completion date
Unknown
Last updated
2023-02-20

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Diabetes

Interventions

Sponsors

Dongzhimen Hospital, Beijing University of Chinese Medicine
Lead Sponsor

Eligibility

Sex/Gender
All
Age
40 Years to 75 Years

Inclusion criteria

Inclusion criteria: ?there were 20 patients who met the diagnostic criteria of type 2 diabetes and TCM criteria for non dampness heat syndrome.? Conforms to the diagnostic criteria of damp heat syndrome of Chinese medicine and one of the diagnostic criteria for obesity or hyperlipidemia, and the subjects have no risk factors for type 2 diabetes, namely, fasting plasma glucose level < 100 mg/dL, glycosylated hemoglobin (HbA1c) < 5.7% (normal glucose metabolism), 20 cases. ? There were 20 healthy people. 40 = age = 75, regardless of gender, sign informed consent.

Exclusion criteria

Exclusion criteria: Patients with primary diseases of heart, liver, kidney, endocrine system or acute and chronic gastrointestinal diseases; Patients with mental illness; Pregnant or lactating patients; Taking drugs that may affect intestinal flora in recent 2 months, such as antibiotics, berberine, defecation drugs, bifidobacteria, etc; Those who had received external enema therapy within 1 month were sampled.

Design outcomes

Primary

MeasureTime frame
Blood sample proteomics;glycosylated hemoglobin;Urinary creatinine;Detection of water molecules in blood samples;urinalysis;routine blood test;Urine sample proteomics;electrocardiogram;Detection of inflammatory factors and cytokines in blood samples;Western blot verification of blood samples;Blood biochemistry;Stool routine;Detection of water molecules in urine samples;Fundus color photograph examination;Fasting and postprandial blood glucose;Metabolomics of urine samples;Tongue color photo examination;Metabolomics of blood samples;Urinary microalbumin;Single cell sequencing of blood samples;Stool sample flora detection;

Countries

China

Contacts

Public ContactLiu hongfang
lhfdoctor@126.com18801175242

Outcome results

None listed

Source: ITMCTR (via WHO ICTRP) · Data processed: Feb 4, 2026