Acute bronchitis cough in children
Conditions
Interventions
control group:take Xiao'er Huangjin Zhike Granules placebo
treatment group:take Xiao'er Huangjin Zhike Granules
Sponsors
Beijing Children's Hospital,Capital Medical University
Eligibility
Sex/Gender
All
Age
3 Years to 7 Years
Inclusion criteria
Inclusion criteria: Inclusion criteria: (1) Consistent with the diagnosis of acute bronchitis in children; (2) TCM syndrome differentiation is syndrome of phlegm heat obstructing lung; (3) Aged between 3 and 7 (including 3 and 7 years old), regardless of gender; (4) Cough symptom score =2 points in daytime or =2 points in night; (5) Within 72 hours after the onset of acute bronchitis, no drugs with antitussive and expectorant effects or other treatments were used before treatment (except for those who only used once or twice and no drugs were used within 12 hours); (6) The legal guardians of the children agreed that their children should participate in the study and sign the informed consent.
Exclusion criteria
Exclusion criteria: Exclusion criteria: (1) The highest body temperature within 24 hours before enrollment & GT; Children at 38.5?; (2) children with measles, whooping cough, influenza and other acute infectious diseases; (3) children with acute upper respiratory tract infection, bronchial asthma, bronchiolitis, asthmatic bronchitis, bronchopneumonia and other respiratory diseases; (4) Children allergic to the test drug or its ingredients; (5) children with malnutrition, immune deficiency and tuberculosis; (6) Children who have participated in or are participating in clinical trials of other drugs within 1 month; (7) children with serious primary diseases such as heart, liver, kidney, digestive and hematopoietic system; (8) The researchers identified children who were not suitable for clinical trials.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Rate of cough disappearance/basic disappearance after 7 days of treatment.; | — |
Secondary
| Measure | Time frame |
|---|---|
| Cough severity-time area under the curve;Cough onset time;Evaluation of sputum viscosity;Cough disappear/almost disappear time;Phlegm symptom score;TCM syndrome effect; | — |
Countries
China
Contacts
Public ContactBaoping XU
Outcome results
None listed