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Transcutaneous acupoint electrical stimulation improves postoperative sleep of patients with gastrointestinal tumors by regulating the Nrf2/ARE signal pathway

Transcutaneous acupoint electrical stimulation improves postoperative sleep of patients with gastrointestinal tumors by regulating the Nrf2/ARE signal pathway

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
ITMCTR
Registry ID
ITMCTR2100005469
Enrollment
Unknown
Registered
2021-12-29
Start date
2021-01-01
Completion date
Unknown
Last updated
2023-02-20

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

gastrointestinal tumor

Interventions

1:TEAS

Sponsors

Xuzhou Traditional Chinese Medicine Hospital Affiliated to Nanjing University of Chinese Medicine
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 75 Years

Inclusion criteria

Inclusion criteria: 1.Patients undergoing elective laparoscopic gastrointestinal tumor surgery 2.Age: 18 to 75 years old 3.American Association of Anesthesiologists (ASA) grade I to III 4.BMI 18.5kg/m2 - 28kg/m2 5.Preoperative clinical tumor TNM staging: cTis-3N0-1M0 (refer to AJCC/UICC 8th edition TNM staging)

Exclusion criteria

Exclusion criteria: 1. PSQI>7 points. 2.Sleep apnea, or moderate or more snoring. 3. Preoperative sinus bradycardia (heart rate less than 50 beats/min) or sinus node disease, second-degree or third-degree atrioventricular block, and pacemaker. 4.Long-term use of anticonvulsants, antidepressants or other psychotropic drugs. 5. Those who are highly sensitive or allergic to the drugs or equipment in this study. 6.Severe heart, liver or kidney disease. 7. Participated in other clinical trials in the past 3 months. 8.Hearing and language communication barriers, unable to communicate effectively with doctors. 9. Patients who are pregnant or breastfeeding. 10.Patients with fever or infection before surgery.11.Patients who live with critically ill patients or live in a ward with> 3 persons.

Design outcomes

Primary

MeasureTime frame
AIS score;PSQI score;

Secondary

MeasureTime frame
HRV physiological data;Time of first air exhaust after operation;Liquid in and out;operation time;VAS score;Anesthesia time;Intraoperative remedies;Intraoperative blood pressure;Analgesic use;Body temperature changes;Hospital stay;Adverse events and medication;

Countries

China

Contacts

Public ContactFeifei Lu
lufei09flg@126.com18795425961

Outcome results

None listed

Source: ITMCTR (via WHO ICTRP) · Data processed: Feb 4, 2026