retinitis pigmentosa
Conditions
Interventions
Sponsors
eye hospital, China Academy of Chinese Medical Sciences
Eligibility
Sex/Gender
All
Age
18 Years to 80 Years
Inclusion criteria
Inclusion criteria: ?Diagnosis of RP; ?Comply with TCM syndrome differentiation of liver and kidney yin deficiency syndrome; ?Age between 18-80 years old; ?Visual acuity of greater than or equal to 35 letters in at least one eye as measured by the EVA-ETDRS (equivalent to 20/200 on a Snellen chart); ?Understand and sign the informed consent document for the study.
Exclusion criteria
Exclusion criteria: ?Medical problems that make consistent follow-up over the treatment period unlikely (e.g. cardio-cerebrovascular, liver, hematopoietic system diseases, or severely life-threatening primary diseases, mental illness or cognitive impairment, etc.); ?Other eye diseases: optic nerve and retinal diseases, glaucoma, ocular autoimmune diseases, ocular surface diseases that affect visual function, etc; ?Subject unable to provide reliable perimetry measurements in both eyes for both static and kinetic visual field, as determined by the Reading Center; ?Suspected liver and kidney dysfunction determined by having alanine aminotransferase (ALT) and aspartate aminotransferase (AST) elevated more than 2 times beyond the normal, and blood creatinine above the upper limit of normal; ?RP patients involved in other clinical trials within the last 3 months, or had taken one of the similar drugs or other therapies that affect the evaluation of efficacy; ?Sensitive to or have ever had an allergic reaction to known ingredients of research drugs; ?Pregnant women and lactating mothers who are breast feeding their babies.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Visual field; | — |
Secondary
| Measure | Time frame |
|---|---|
| Electroretinogram;Visual acuity;TCM syndrome scoring; Visual function questionnaire scoring; | — |
Countries
China
Contacts
Public ContactGuojun Chao
Outcome results
None listed