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Evaluation value of medullary cell trigger receptor (TREM) in the prognosis of Idiopathic facial paralysis and clinical study of microneedle knife combined with acupuncture intervention

Evaluation value of medullary cell trigger receptor (TREM) in the prognosis of Idiopathic facial paralysis and clinical study of microneedle knife combined with acupuncture intervention

Status
Active, not recruiting
Phases
Early Phase 1
Study type
Interventional
Source
ITMCTR
Registry ID
ITMCTR2100005400
Enrollment
Unknown
Registered
2021-12-12
Start date
2021-12-13
Completion date
Unknown
Last updated
2023-02-20

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

idiopathic facial nerve palsy

Interventions

Microneedle knife combined with acupuncture group:Microneedle knife combined with acupuncture

Sponsors

Zhejiang hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 75 Years

Inclusion criteria

Inclusion criteria: 1.Meet the diagnostic criteria for Bell paralysis 2: Receive standardized treatment of Western medicine 3: Age 18-75, lesion is on one side, and the course of the disease is less than 3 months 4: Voluntary participation in this study and signing an informed consent form

Exclusion criteria

Exclusion criteria: 1: Patients with central facial neuritis and peripheral facial neuritis caused by other diseases (traumatic trauma, tumor, otitis media, acoustic neuroma surgery, facial neuroma, Green Barre syndrome, etc.); those with sequelae of previous facial paralysis 2: People with severe primary diseases such as diabetic neuropathy, heart, cerebrovascular, liver, kidney, lung and hematopoietic system and mental patients have low blood and coagulation mechanisms; patients with a a history of dizziness needles and halo 3: Lyme disease, facial spasm, pregnant or lactating women and allergic constitutions

Design outcomes

Primary

MeasureTime frame
House-Brackmann facial nerve function evaluation scale;

Secondary

MeasureTime frame
SDS;Grading scale of facial paralysis;Facial Disability Index (FDI) Scale;Facial electrograph examination;SAS;Immune inflammation-related indicators;SF-36 Quality of Life Evaluation Scale;

Countries

China

Contacts

Public ContactYidan Chen
chenyidan0908@vip.126.com13221067998

Outcome results

None listed

Source: ITMCTR (via WHO ICTRP) · Data processed: Feb 4, 2026