gout
Conditions
Interventions
Control group:Benbromarone tablets (50mg/ tablet *30/ box, manufacturer: Kunshan Longdeng Ruidi Pharmaceutical Co., LTD.), one tablet every time, once a day, for consecutive 12 weeks
Sponsors
Yunnan Hospital of Traditional Chinese Medicine
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: (1) It met the diagnostic criteria of primary gout and was in an intermittent period, and the syndrome was spleen deficiency and dampness resistance;(2) Aged between 18 and 65;(3) Did not take uric-lowering drugs, did not participate in clinical studies, or stopped eluting drugs for more than 6 months after participating in clinical studies;(4) No gastrointestinal diseases, antibiotics, gastrointestinal motility drugs or probiotics in the past 2 months;(5) Take the test voluntarily and sign the consent form.
Exclusion criteria
Exclusion criteria: (1) Secondary hyperuricemia caused by other diseases and treatment methods;(2) those who are using drugs that affect uric acid metabolism, such as salicylate, furosemide and thiazide diuretics;(3) those who have been allergic to the drug components used in this study, or are prone to allergic phenomenon;(4) Patients suffering from cardiovascular diseases or serious primary diseases of other organs and systems;(5) persons suffering from mental diseases;(6) women in pregnancy or lactation, or those who need to prepare for pregnancy;(7) overlap with other rheumatic diseases;(8) Those who plan to undergo surgery recently;(9) persons who are addicted to alcohol, drugs or drugs;(10) taking antibiotics, probiotics and prebiotics in the last two months;(12) Exclude metabolic diseases (especially those affecting the intestinal flora).
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| intestinal microflora; | — |
Contacts
Public ContactPeng Jiangyun
Outcome results
None listed