amnestic mild cognitive impairement
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1. Subjects meeting the diagnostic criteria of aMCI; 2. Subjects aged 55-70 years; 3. Subjects with middle school education or above; 4. The objects who have been proved to be healthy by physical examination in the third grade a hospital in the past half a year; 5. Subjects with body mass index (BMI) in the range of 20-24; 6. All of them are right handed; Subjects participated voluntarily and signed informed consent.
Exclusion criteria
Exclusion criteria: 1. Objects with metal residues and tattoos in the body;Objects with or suspected brain lesions; 2. Objects who are afraid of MRI or can not be scanned by MRI for other reasons; 3. The object of heavy drinking and drug abuse; 4. Patients with mental history or congenital mental retardation; patients who are taking anti anxiety or anti depression drugs and receiving psychological treatment in the past 3 months; 5. Patients with serious heart, liver and kidney diseases; 6. Patients with other diseases of the nervous system that can cause cognitive dysfunction, such as brain tumor, encephalitis, epilepsy, Parkinson's disease, etc.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Cognitive function; | — |
Secondary
| Measure | Time frame |
|---|---|
| Episodic memory;Working memory;Cognitive related fMRI data;Safety indicators;EEG data;Quality of life assessment; | — |
Countries
China