colorectal cancer
Conditions
Interventions
Maintenance treatment period + Quxie Capsule:Maintenance treatment + Quxie Capsule
Single drug chemotherapy or targeted therapy + Quxie Capsule:Single drug chemotherapy or targeted therapy + Quxie Capsule
Standard chemotherapy period + Quxie Capsule:Standard chemotherapy + Quxie Capsule
Simple TCM treatment period + Quxie Capsule:Simple TCM treatment + Quxie Capsule
Sponsors
Xiyuan Hospital, China Academy of Chinese Medical Sciences
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: 1. Over 18 years old, regardless of gender; 2. Colorectal cancer diagnosed by pathology; 3. The clinical stage is stage IV; 4. ECoG 0-2 points; 5. Estimated survival time = 3 months; 6. Measurable lesions meeting RECIST 1.1 standard; 7. Voluntarily join the study and sign the informed consent form; 8. Those with good compliance are expected to follow up the efficacy and adverse reactions according to the protocol requirements.
Exclusion criteria
Exclusion criteria: 1. Patients whose clinical stage is IVA stage and who have the opportunity of radical surgery or potential transformation; 2. Diarrhea > 3 times / day, or diarrhea of grade II or above (CTCAE v4.03 grade); 3. Complicated with severe cardiovascular system complications, cerebrovascular system complications, active hepatitis and severe liver and kidney dysfunction; 4. There are many factors affecting the absorption of oral drugs, such as inability to swallow and intestinal obstruction; 5. Any unstable situation or situation that may endanger the safety of patients and their compliance with the study, such as schizophrenia and other serious mental diseases; 6. Patients who will or are participating in other clinical trials;
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Overall survival; | — |
Secondary
| Measure | Time frame |
|---|---|
| Objective response rate;Disease control rate;Progression free survival; | — |
Countries
China
Contacts
Public ContactYang-Yufei
Outcome results
None listed