Chronic Obstructive Pulmonary Disease
Conditions
Interventions
Control group:placebo
Experimental group:Jian Pi Shu Fei granules
Sponsors
Guangdong Provincial Hospital of Chinese Medicine
Eligibility
Sex/Gender
All
Age
40 Years to 85 Years
Inclusion criteria
Inclusion criteria: ?Patients who are aged 40–85 years; ?Patients who meet the diagnostic criteria of COPD, stage I-II, with stable stage; ?Patients who meet the Chinese medicine syndrome classification of Qi deficiency and phlegm obstruction; ?Patients who sign the written informed consent form.
Exclusion criteria
Exclusion criteria: ?Patients with asthma,bronchiectasis,obstructive sleep apnea syndrome,lung malignant tumors or active pulmonary tuberculosis;?Chinese medicine syndrome based on Yin deficiency;?Patients with acute exacerbation of COPD within 4 weeks before enrollment;?Patients with history of allergies or hypersensitivity for any research drug component, or the researcher believes that it is known to have a disease that should not be participated in research;?Those who cannot complete the lung function test; ?Long-term of traditional Chinese medicine diet (astragalus, ginseng) and other Chinese medicinal materials);?Patients with severe cardiovascular, cerebrovascular, liver and kidney disease;?Alanine aminotransferase (ALT), aspartate aminotransferase (AST) or serum creatinine (Scr) exceed 1.5 times the upper limit of normal value;?Poor compliance;?Patients who have received any experimental drug treatment within 1 month;?Patients who Participated in or plan to participate in other clinical trials.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| CAT; | — |
Secondary
| Measure | Time frame |
|---|---|
| Acute exacerbation per year;Safety;BODE;Time to first exacerbation;mMRC;CCQ;6MWT;CASA;lung function; | — |
Countries
China
Contacts
Public ContactLin Lin
Outcome results
None listed