compensation period for liver cirrhosis related to hepatitis B
Conditions
Interventions
Test group :combination therapy with Bie Jia Ruan Gan Jian Pi Fang and Entecavir
Sponsors
TCM-Integrated Hospital of Southern Medical University
Eligibility
Sex/Gender
All
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: (1)meet the western medical diagnostic criteria for the compensation period for liver cirrhosis related to hepatitis B; (2)meet the diagnostic criteria for Chinese medicine for Gan Dan Shi Re Jia Yu;(3)meet the antiviral standards for hepatitis B;(4)not use any antiviral drugs other than Entecavir within 3 months of diagnosis;(5)age 18-65 years old at the time of diagnosis, gender unlimited;(6)Informed consent and treatment and treatment-related laboratory examination, and can answer questions truthfully.
Exclusion criteria
Exclusion criteria: (1) Testing for sero HIV; (2) combining other viral liver diseases, non-alcoholic fatty hepatitis, explicit drug-damaging liver disease, self-free liver and other chronic liver diseases; (3) the combination of other chronic severe hepatitis, liver cirrhosis, liver cancer and other serious or terminal liver disease; (4) other diseases seriously affect their quality of life. If there are severe organ dysfunction and severe diabetes, liver and kidney syndrome, liver and lung syndrome or other severe trauma caused by liver disease;
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| fibroscan;color Doppler ultrasound of liver, bile, pancreas and spleen; | — |
Secondary
| Measure | Time frame |
|---|---|
| liver function;Symptom & Signs;serum indices of hepatic fibrosis;HBV marker;APRI score;FIB-4 score;HBV-DNA; | — |
Countries
China
Contacts
Public ContactSongqi He
TCM-Integrated Hospital of Southern Medical University
Outcome results
None listed