Primary Hypertension
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1. Age 35-80 (including 35 and 80), gender is not limited 2. According to the Chinese Guidelines for the Prevention of Hypertension (Revised 2018),Patients diagnosed with primary hypertension levels 1-2 3. Understand and sign informed consent form Note: The above three items must be met at the same time before they can be included in the study.
Exclusion criteria
Exclusion criteria: 1. In contraindications of anti-pulse therapy :Hypertension grade 2 or higher; severe heart failure, 1 month history of heart infarction, severe aortic valve insufficiency, atrial fibrillation and frequent ventricular velocity. 2. Take medication that affects blood pressure fluctuations: e.g. have been taking birth control pills for less than three months. 3. Secondary hypertension: renal parenchyma and renal vascular hypertension, endocrine hypertension, aortic constriction, obstructive sleep apnea hypoventilation syndrome, pharmacogenic hypertension (including female contraceptives, eugene, partial diet pills, left dopa, non-dixie drugs, glucocorticoids, partial immunosuppressants, erythropoietin, etc.). 4. Unable or unwilling to comply with the study plan Note: any items that meet the requirements should be excluded.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| vascular endothelial growth factor indicators;24 Hour Ambulatory Blood Pressure Monitoring;The change of mean SBP and DBP at the end of interventiona compares to the baseline.; | — |
Secondary
| Measure | Time frame |
|---|---|
| Serum Biochemical Indicators;carotid-femoral pulse wave velocity; | — |
Countries
China