Infertility
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: ? Meet the diagnostic criteria for infertility: Both spouses have normal sexual life and have not been pregnant for 1 year without contraception; ? Patients who intend to receive IVF-ET treatment in Shuguang Hospital, aged between 35-42 years old; ? Meet the diagnostic criteria of TCM kidney essence deficiency type; Diagnostic criteria for infertility due to deficiency of kidney essence: (Refer to the Twelfth Five-Year Plan Planning textbook "Chinese Medicine Gynecology" and higher medical college textbook "Chinese Medicine Diagnostics" 5th edition) Main symptoms: long-term marriage, infertility, irregular menstruation, low menstrual flow, pale color, or even amenorrhea. Secondary symptoms: weakness in the waist and knees, dizziness, tinnitus, decreased libido, fatigue, forgetfulness and hair loss. Tongue and pulse: pale red tongue, white coating, deep and thin pulse. With long-term marriage and infertility, the main symptom has 1 item, and the secondary symptom has 1-2 items, which can be diagnosed by referring to the tongue and pulse. ? Sign the informed consent form.
Exclusion criteria
Exclusion criteria: ? Those who do not meet the diagnostic criteria; ? Those who have ovarian dysfunction caused by taking hormones, immunosuppressive drugs, radiotherapy and chemotherapy for malignant ovarian tumors; ? Patients with severe primary diseases such as severe cardiovascular, liver, kidney and hematopoietic system.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Expression of Related Gene Proteins in GV Stage Oocytes;Clinical pregnancy rate; | — |
Countries
China