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Based on SAC's regulation mechanism of E3 ligase APC/CCDC20 to study the effect and mechanism of electroacupuncture on egg aging

Based on SAC's regulation mechanism of E3 ligase APC/CCDC20 to study the effect and mechanism of electroacupuncture on egg aging

Status
Recruiting
Phases
Early Phase 1
Study type
Interventional
Source
ITMCTR
Registry ID
ITMCTR2100005352
Enrollment
Unknown
Registered
2021-11-29
Start date
2021-12-01
Completion date
Unknown
Last updated
2023-02-20

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Infertility

Interventions

Electroacupuncture group:Electroacupuncture+IVF-ET

Sponsors

Shuguang Hospital Affiliated to Shanghai University of Traditional Chinese Medicine
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
35 Years to 42 Years

Inclusion criteria

Inclusion criteria: ? Meet the diagnostic criteria for infertility: Both spouses have normal sexual life and have not been pregnant for 1 year without contraception; ? Patients who intend to receive IVF-ET treatment in Shuguang Hospital, aged between 35-42 years old; ? Meet the diagnostic criteria of TCM kidney essence deficiency type; Diagnostic criteria for infertility due to deficiency of kidney essence: (Refer to the Twelfth Five-Year Plan Planning textbook "Chinese Medicine Gynecology" and higher medical college textbook "Chinese Medicine Diagnostics" 5th edition) Main symptoms: long-term marriage, infertility, irregular menstruation, low menstrual flow, pale color, or even amenorrhea. Secondary symptoms: weakness in the waist and knees, dizziness, tinnitus, decreased libido, fatigue, forgetfulness and hair loss. Tongue and pulse: pale red tongue, white coating, deep and thin pulse. With long-term marriage and infertility, the main symptom has 1 item, and the secondary symptom has 1-2 items, which can be diagnosed by referring to the tongue and pulse. ? Sign the informed consent form.

Exclusion criteria

Exclusion criteria: ? Those who do not meet the diagnostic criteria; ? Those who have ovarian dysfunction caused by taking hormones, immunosuppressive drugs, radiotherapy and chemotherapy for malignant ovarian tumors; ? Patients with severe primary diseases such as severe cardiovascular, liver, kidney and hematopoietic system.

Design outcomes

Primary

MeasureTime frame
Expression of Related Gene Proteins in GV Stage Oocytes;Clinical pregnancy rate;

Countries

China

Contacts

Public ContactZhong Xiufang
zhongxiufang@hotmail.com18721652872

Outcome results

None listed

Source: ITMCTR (via WHO ICTRP) · Data processed: Feb 4, 2026