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Oral Tanshinone in the treatment of dry eye associated with rosacea

Oral Tanshinone in the treatment of dry eyes associated with rosacea

Status
Active, not recruiting
Phases
Early Phase 1
Study type
Interventional
Source
ITMCTR
Registry ID
ITMCTR2100005326
Enrollment
Unknown
Registered
2021-09-20
Start date
2021-10-01
Completion date
Unknown
Last updated
2023-02-20

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

dry eye associated with rosacea

Interventions

test group:Daily oral tanshinone

Sponsors

The Second Affiliated Hospital of Fujian Medical University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 60 Years

Inclusion criteria

Inclusion criteria: This study included patients who were diagnosed with rosacea at the dermatology clinic and met the ophthalmologic assessment for dry eye.

Exclusion criteria

Exclusion criteria: 1.Trichiasis, eyelid abnormalities, lacrimal diseases, glaucoma or Uveitis, and other ophthalmic emergencies; 2.Other conjunctival or ocular surface diseases, such as conjunctival cyst, conjunctival pemphigoid, conjunctival relaxation, limbal stem cell deficiency, etc. 3.long-term use of topical drugs in addition to artificial tears, such as anti-glaucoma drugs, immunosuppressants, etc. 4.History of ocular trauma, eyelid, ocular surface, glaucoma and internal eye surgery; 5.Severe liver and kidney dysfunction, Coagulopathy, or other serious diseases may affect drug efficacy; 6.Pregnant women; 7.The researchers concluded that there were any conditions that were not suitable for participation in the trial.

Design outcomes

Primary

MeasureTime frame
Corneal sodium fluorescein staining;Non-invasive tear film breakup time;meibomian gland dropout;Schiemer I test;plugged meibomian gland orifices;

Countries

China

Contacts

Public ContactYingying Gao

The Second Affiliated Hospital of Fujian Medical University

gaoyingying1968@163.com13305960006

Outcome results

None listed

Source: ITMCTR (via WHO ICTRP) · Data processed: Feb 4, 2026