advanced colon cancer
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1. Age 18-80, no gender limitation; 2. Patients with tumor whose clinical stage was stage IV and could not be radically resected. 3. No previous chemotherapy; 4. Quality of Life Score (KPS Score) =60; 5. The expected survival time is more than 6 months; 6. Good compliance; informed consent was signed before enrollment; 7. Patients agree not to participate in other intervention studies during treatment.
Exclusion criteria
Exclusion criteria: 1. Those with specific targeted therapy through genetic testing; 2. Patients with other primary malignant tumors; 3. Patients with serious complications of cardiovascular system, cerebrovascular system, active hepatitis, and serious liver and kidney dysfunction that can't tolerate chemotherapy; 4. Patients with severe bleeding tendency who cannot use bevacizumab; 5. Those who have received first-line chemotherapy or above; 6. Patients receiving other immunotherapy; 7. Allergic to the test drug; 8. Women during lactation and pregnancy; 9. Those who cannot comply with the requirements of the scheme or experiment; 10. People with severe mental illness, bad fluid, and can't cooperate with treatment; 11. Used other Proprietary Chinese medicines with anti-tumor and improved immunity.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| DCR;PFS; | — |
Secondary
| Measure | Time frame |
|---|---|
| immunologic function;quality of life;tumor marker;assessment of the safety; | — |
Countries
China