Knee Osteoarthritis
Conditions
Interventions
Sponsors
Jiangsu Provincial Cadre's Sanatorium
Eligibility
Sex/Gender
All
Age
40 Years to 75 Years
Inclusion criteria
Inclusion criteria: (1) Meet the diagnostic criteria for knee osteoarthritis of the American Academy of Rheumatology; (2) In most days of the past month, knee joint pain was at least moderate or below (pain numerical score method, namely VAS score<7); (3) Age 40-75 years old (including 40 and 75 years old); (4) Subjects stop analgesics and only allow them to take related drugs when the pain is unbearable, such as analgesics or non-steroidal anti-inflammatory drugs. But subjects cannot take hormone drugs; (5) Willing to sign an informed consent form. Note: Patients who meet the above 5 items at the same time can be included in this study.
Exclusion criteria
Exclusion criteria: (1) Those who have received hormone therapy in the past 3 months; (2) Receive intra-articular hyaluronidase injections within the past 6 months; (3) Received joint irrigation or arthroscopy in the past year; (4) Diseases that hinder the safe participation of experimental design and the completion of the research, such as severe systemic diseases such as myocardial infarction or stroke, congestive heart failure, severe chronic obstructive pulmonary disease, cancer, diabetes, etc. in the past 3 months. Severe mental illness; (5) Physical history or clinical manifestations with bleeding tendency, including the current use of anticoagulants; (6) Inflammatory arthritis (such as rheumatoid or psoriasis), this trial will test subjects for rheumatoid factor, erythrocyte sedimentation rate, and anti-O to exclude the possibility of rheumatoid arthritis (7) Participate in other research at the same time; (8) Those who have had knee replacement surgery; (9) Participated in the related treatment of knee osteoarthritis trial in the past; (10) Those who are excessively fearful of needle knives; (11) At the same time local use of external treatment methods, such as local application treatment, etc.; (12) Unable to complete various scales; (13) Unwilling to be randomly grouped. Note: Patients who meet any of the above items will be excluded.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| IL-1\IL-17\TNF-a\OPG\PCTBGP\; | — |
Countries
CHINA
Contacts
Public ContactWANGPei
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Outcome results
None listed