Sepsis
Conditions
Interventions
Sponsors
Longhua Hospital Shanghai University of Traditional Chinese Medicine
Eligibility
Sex/Gender
All
Age
18 Years to 80 Years
Inclusion criteria
Inclusion criteria: 1.According to sepsis 3.0 diagnostic criteria; 2.Aged >= 18 and <=80 years; 3.Sign informed consent.
Exclusion criteria
Exclusion criteria: 1.The time of definite diagnosis of sepsis was more than 48 hours; 2.Pregnant and lactating women; 3.Serious primary diseases that affect survival, including failed to control multiple metastases that could not be resected, hematological diseases, HIV, etc.; 4.Patients with liver or kidney dysfunction whose SOFA score of liver or kidney was more than 3; 5.Persistent use of immunosuppressants or organ transplantation in the past 6 months; 6.Patients had been treated with hormone continuously for 7 days before entering the group and converted to methylprednisolone dose>=20mg/day; 7.Patients participated in other clinical trials within 30 days; 8.The patients were in critical condition (sofa>=15 or APACHE II>=30) and/or refused active treatment; 9.Known to be allergic to Xuebijing or allergic constitution.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| SOFA score improvement; | — |
Secondary
| Measure | Time frame |
|---|---|
| 28 day all cause mortality;Duration of mechanical ventilation;Length of stay in ICU;APACHE II score improvement; | — |
Countries
China
Contacts
Public ContactFang Bangjiang
Longhua Hospital Shanghai University of Traditional Chinese Medicine
Outcome results
None listed