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Clinical study of rhubarb combined with percutaneous electrical stimulation to improve acute gastrointestinal injury in patients with sepsis

Clinical study of rhubarb combined with percutaneous electrical stimulation to improve acute gastrointestinal injury in patients with sepsis

Status
Active, not recruiting
Phases
Early Phase 1
Study type
Interventional
Source
ITMCTR
Registry ID
ITMCTR2100005286
Enrollment
Unknown
Registered
2021-09-08
Start date
2021-09-10
Completion date
Unknown
Last updated
2023-02-20

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

sepsis

Interventions

PES+rhubarb group:PES+rhubarb
Control group:Conventional treatment
PES group:Percutaneous electrical stimulation

Sponsors

Affiliated Hospital of Jiangsu University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 80 Years

Inclusion criteria

Inclusion criteria: ? Older than 18 and younger than 80 years old; ? Patients admitted to ICU; ? Meet the diagnostic criteria of sepsis 3.0; ? Meet AGI diagnostic criteria, and grade is I, II, III; ? Patients or their family members signed informed consent and cooperated with the investigation with good compliance.

Exclusion criteria

Exclusion criteria: ? Gastrointestinal perforation, intestinal obstruction, gastrointestinal surgery, intestinal fistula and other contraindications of enteral nutrition ? Patients with skin infection, ulcers and scars are not suitable for acupoint electrical stimulation treatment ? AGI: level IV ? The patients are endangered and their expected survival time is less than 5 days ? Patients with impaired immune function or undergoing immunotherapy ? Pregnant women ? Are participating in other clinical trials ? Patients refused to participate in the study

Design outcomes

Primary

MeasureTime frame
Time for enteral nutrition to reach standard;target-reach of EN at day 7;Regular bowel sounds recovery time;Antral motility index;

Secondary

MeasureTime frame
Prognostic indicators;Intestinal mucosal permeability index;Infection index;Nutrition indicators;Gastrointestinal motility index;The immune indexes;Inflammation levels;

Countries

China

Contacts

Public ContactYin jiangtao
doctoryjt2438@163.com13952943135

Outcome results

None listed

Source: ITMCTR (via WHO ICTRP) · Data processed: Feb 4, 2026