Stroke
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: ? In line with the 2018 edition of China's guidelines for the diagnosis and treatment of acute ischemic stroke; ? No obvious cognitive impairment (MMSE = 25); ? The first onset was confirmed by cranial CT or MRI. The course of disease was stable within 2 weeks to 3 months, ? There was unilateral upper limb hand motor dysfunction in Brunnstrom ? ~ V phase of upper limb; ? Age 18-80 years old, regardless of gender; ? The informed consent of this study shall be read and signed by the patient or his/her directly-related members of family.
Exclusion criteria
Exclusion criteria: ? Severe spasm (MAS > 2 points); ? Obvious pain in hemiplegic limbs (VAS score > 4); ? Obvious sensory dysfunction, aphasia, unilateral neglect, apraxia or audiovisual impairment; ? Complicated with epilepsy or severe heart, liver, kidney, hematopoietic system and other important organ failure; ? There are contraindications to TMS, including metal foreign bodies in the head, pacemakers, cardiac stents, cochlear implants, and significantly increased intracranial pressure; ? History of alcohol or drug abuse; ? Those who cannot complete the basic course of treatment and may have poor compliance ? non local patients cannot be followed up.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| FMA-UE; | — |
Secondary
| Measure | Time frame |
|---|---|
| Modified Barthel Index,MBI;TMS assessment;Montreal Cognitive Assessment, MoCA;Boxing and Blocking Test;MAS; | — |
Countries
China